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Protein Overview: stg-PA, FBpp0306890

General Information:
Name(s) found: FBpp0306890 [FlyBase]
stg-PA / FBpp0084766 [FlyBase]
Description(s) found:
Found 31 descriptions.
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  • type=protein; loc=3R:complement(25078300..25079683,25080595..25080650); ID=FBpp0306890; name=stg-PB; parent=FBgn0003525,FBtr0334867; dbxref=FlyBase:FBpp0306890,FlyBase_Annotation_IDs:CG1395-PB,REFSEQ:NP_001263066,GB_protein:AGB96446; MD5=0a5f9b507cb190d7cfb37e943e75150f; length=479; release=r5.56; species=Dmel; [FlyBase]
  • The gene string is referred to in FlyBase by the symbol Dmel\stg (CG1395, FBgn0003525). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:25077540..25081502. It has the cytological map location 99A5. There is experimental evidence that it has the molecular function</span>: protein tyrosine phosphatase activity. There is experimental evidence that it is involved in the biological process</span>: protein amino acid dephosphorylation; cellular process; regulation of mitotic cell cycle; gastrulation; centriole replication; cell cycle; G2/M transition of mitotic cell cycle. 127 alleles are reported. The phenotypes of these alleles are annotated with 48 unique terms, many of which group under: peripheral nervous system; nervous system; embryonic nervous system; organ system; adult segment; imaginal precursor; external compound sense organ; adult mesothoracic segment; nuclear part; embryonic neuron; cell cycle. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 479 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    chromosome [IDA]
    Biological Process: M phase of mitotic cell cycle [IEA]
    G2/M transition of mitotic cell cycle [IMP][ISS][NAS][TAS]
    centriole replication [IMP]
    regulation of mitosis [NAS]
    protein amino acid dephosphorylation [IDA][NAS]
    mesoderm development [TAS]
    peripheral nervous system development [TAS]
    regulation of mitotic cell cycle [IMP]
    cell cycle [IMP]
    cellular process [IMP]
    gastrulation [IMP][NAS]
    open tracheal system development [TAS]
    Molecular Function: non-membrane spanning protein tyrosine phosphatase activity [NAS]
    protein tyrosine phosphatase activity [IDA]
    protein tyrosine/serine/threonine phosphatase activity [NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLWETIVEEN NCSMDCNISN NTSSSSSINK MSGSRRARRS LELMSMDQEE LSFYDDDVVP  60
   61 QDQQRSASPE LMGLLSPEGS PQRFQIVRQP KILPAMGVSS DHTPARSFRI FNSLSSTCSM 120
  121 ESSMDDEYME LFEMESQSQQ TALGFPSGLN SLISGQIKEQ PAAKSPAGLS MRRPSVRRCL 180
  181 SMTESNTNST TTPPPKTPET ARDCFKRPEP PASANCSPIQ SKRHRCAAVE KENCPAPSPL 240
  241 SQVTISHPPP LRKCMSLNDA EIMSALARSE NRNEPELIGD FSKAYALPLM EGRHRDLKSI 300
  301 SSETVARLLK GEFSDKVASY RIIDCRYPYE FEGGHIEGAK NLYTTEQILD EFLTVQQTEL 360
  361 QQQQNAESGH KRNIIIFHCE FSSERGPKMS RFLRNLDRER NTNAYPALHY PEIYLLHNGY 420
  421 KEFFESHVEL CEPHAYRTML DPAYNEAYRH FRAKSKSWNG DGLGGATGRL KKSRSRLML

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..246] MSA 3.139994 View MSA. No confident structure predictions are available.
    2 View Details [247..479] PSI-BLAST 69.045757 CDC25b

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • phosphoprotein phosphatase activity
    		•  4.79074052803751 bayes_pls_golite062009
  • phosphatase activity
    		•  3.95816335500141 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  3.78173224935267 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  3.24681684836294 bayes_pls_golite062009
  • protein tyrosine phosphatase activity
    		•  2.84204105189999 bayes_pls_golite062009
  • hydrolase activity
    		•  2.12055507229256 bayes_pls_golite062009
  • binding
    		•  1.72957395505299 bayes_pls_golite062009
  • catalytic activity
    		•  0.687308230067573 bayes_pls_golite062009
  • protein binding
    		•  0.515609053278812 bayes_pls_golite062009
  • transferase activity
    		•  0.302497611306574 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle