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Protein Overview: CG14508-PA

General Information:
Name(s) found: CG14508-PA / FBpp0084775 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG14508 (CG14508, FBgn0039651). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:25028387..25029855. It has the cytological map location 99A1. Based on sequence similarity, it is predicted to have molecular function</span>: electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: mitochondrial electron transport, ubiquinol to cytochrome c; oxidative phosphorylation. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 344 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial respiratory chain complex III [ISS]
    Biological Process: oxidative phosphorylation [ISS]
    mitochondrial electron transport, ubiquinol to cytochrome c [ISS]
    Molecular Function: electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity [ISS]
    heme binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANKFRSLNS KLFQLAMSGI QRTSVRPRIS FPGRGSGFTG NRKLLGALGA LTGTAGLLIY  60
   61 ALETSVDASS DCVHPAHQHW NHKGLLSALD KESVRRGYTV YKEVCSSCHS LQYMAYRNLV 120
  121 GVCMTEAEAK AEAEAITVRD GPNEEGEYYE RPGKLSDHFP SPYANEEAAR SANNGSYPPD 180
  181 LSYIVSARKG GEDYVFSLLT GYCDPPAGFA LRDGLYFNPY FSGGAIAMGK VVDNEVVSFE 240
  241 DPNVPASAAQ IAKDVCVFLK WTSEPETDER RLLLIKVTLI STFLIGISYY IKRFKWSTLK 300
  301 SRKIFFIPEL EAQAKREAEE AAKAARKAKE QECNKCENQN EKKD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..344] PSI-BLAST 95.045757 Cytochrome bc1 domain; Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ubiquinol-cytochrome-c reductase activity
    		•  9.78686808279934 bayes_pls_golite062009
  • oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor
    		•  9.78686808279934 bayes_pls_golite062009
  • electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity
    		•  7.65479843528878 bayes_pls_golite062009
  • oxidoreductase activity, acting on diphenols and related substances as donors
    		•  6.402093715172 bayes_pls_golite062009
  • electron carrier activity
    		•  5.89393941749361 bayes_pls_golite062009
  • oxidoreductase activity
    		•  4.80453374142732 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  3.95927872883558 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  3.81941996826271 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  3.28855051034616 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  3.12657801391409 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.97300461435278 bayes_pls_golite062009
  • electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity
    		•  2.70428810192389 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.64574194038684 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.51612623656281 bayes_pls_golite062009
  • binding
    		•  0.972223231507636 bayes_pls_golite062009
  • oxidoreductase activity, acting on peroxide as acceptor
    		•  0.95569494562262 bayes_pls_golite062009
  • peroxidase activity
    		•  0.95569494562262 bayes_pls_golite062009
  • antioxidant activity
    		•  0.72039892017668 bayes_pls_golite062009
  • protein binding
    		•  0.180623301978971 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle