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Protein Overview: mfrn-PA

General Information:
Name(s) found: mfrn-PA / FBpp0084635 [FlyBase]
Description(s) found:
Found 23 descriptions.
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  • The gene mitoferrin is referred to in FlyBase by the symbol Dmel\mfrn (CG4963, FBgn0039561). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:23768511..23773731. It has the cytological map location 98B6. Based on sequence similarity, it is predicted to have molecular function</span>: iron ion transmembrane transporter activity; transmembrane transporter activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: mitochondrial iron ion transport. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 379 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDA]
    mitochondrial envelope [ISS]
    mitochondrial inner membrane [ISS]
    Biological Process: transmembrane transport [IEA]
    mitochondrial iron ion transport [ISS]
    Molecular Function: transmembrane transporter activity [ISS]
    iron ion transmembrane transporter activity [ISS]
    binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNIDDYESLP TTSVGVNMTA GAIAGVLEHV VMYPLDSVKT RMQSLSPPTK NMNIVSTLRT  60
   61 MITREGLLRP IRGASAVVLG AGPAHSLYFA AYEMTKELTA KFTSVRNLNY VISGAVATLI 120
  121 HDAISSPTDV IKQRMQMYNS PYTSVVSCVR DIYKREGFKA FYRAYGTQLV MNLPYQTIHF 180
  181 TTYEFFQNKM NLERKYNPPV HMAAGAAAGA CAAAVTTPLD VIKTLLNTQE TGLTRGMIEA 240
  241 SRKIYHMAGP LGFFRGTTAR VLYSMPATAI CWSTYEFFKF YLCGLDADQY KSSITGSSEP 300
  301 RKADYVLPRT TDEEQIDQER EAAKEKDTTA TLHSAPTSVN ASGAIKTVCE LSTRPAGPTI 360
  361 NLHTRHTDVK SPYERGFST

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..284] PSI-BLAST 70.522879 structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside
    2 View Details [285..379] MSA 3.161989 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.37

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle