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Protein Overview: CG6074-PA

General Information:
Name(s) found: CG6074-PA / FBpp0084503 [FlyBase]
Description(s) found:
Found 18 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG6074 (CG6074, FBgn0039486). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:22928843..22931906. It has the cytological map location 97E2. Based on sequence similarity, it is predicted to have molecular function</span>: carbonate dehydratase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: one-carbon metabolic process. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 311 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: one-carbon metabolic process [IEA]
    Molecular Function: zinc ion binding [IEA]
    carbonate dehydratase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLTAFLEAS FLLICWSQAV SSHVFGYSEP NQRRWARHHG HCAGKTQSPI AITTSRTTAI  60
   61 HMPAVDMIGY HNLLPYPLKM INNGHTVSIT IPKVNVTEVG EDFLPYIRGA KLPGEFEVEG 120
  121 LHFHWGDKNN RGSEHVINDI RYTMEMHIVH RNKKYATIGE ALNHPDGAAV LGFFFNLDED 180
  181 EGAGLVTINR HLHLIADANQ EATLNVTFSL SSLIAGVDVD KFYTYKGSLT TPPCSEAVTW 240
  241 ILFPDPIPIS PKQISRFRQL SDTQDGALVD NFRTLQPVGN RRIFARTGHV RHTSIATLKH 300
  301 EGEYLKYDWF Y

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..311] PSI-BLAST 81.69897 HUMAN CARBONIC ANHYDRASE II [HCAII] (E.C.4.2.1.1) MUTANT WITH ALA 65 REPLACED BY THR (A65T)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.59667704693142 bayes_pls_golite062009
  • protein binding
    		•  1.30419076438266 bayes_pls_golite062009
  • zinc ion binding
    		•  0.744428270762821 bayes_pls_golite062009
  • transition metal ion binding
    		•  0.36067052386032 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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