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Protein Overview: Sld5-PA

General Information:
Name(s) found: Sld5-PA / FBpp0084348 [FlyBase]
Description(s) found:
Found 26 descriptions.
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  • The gene Sld5 is referred to in FlyBase by the symbol Dmel\Sld5 (CG14549, FBgn0039403). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:21879955..21882213. It has the cytological map location 96F10. There is experimental evidence that it has the molecular function</span>: 3'-5' DNA helicase activity. There is experimental evidence that it is involved in the biological process</span>: positive regulation of S phase of mitotic cell cycle. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 228 amino acids

    Gene Ontology:
    Cellular Component: GINS complex [IDA]
    Biological Process: positive regulation of S phase of mitotic cell cycle [IMP]
    Molecular Function: 3'-5' DNA helicase activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDVEDVPET QLEIDVSDGA GLEDEDDDDM EQITAQKVLE IIETAWINEM CAPEILPSQT  60
   61 DMLELMVSQV AHMEEQMRDL DKNDFRAVVH SMELERVRYI MASYLRCRLQ KIETFTQHIL 120
  121 NQEESREPDD KRLSPEETKF AQEFASNVDE YFHKVATQYM PNQQRGEAEQ RIVTPNLMSH 180
  181 VFLKANVAVP AVIVGVDDEE VDMAAGSQHI IPYQLVADLI QNNQAQLI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..228] PSI-BLAST 61.154902 No description for 2e9xD was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 3'-5' DNA helicase activity
    		•  2.73617158646595 bayes_pls_golite062009
  • binding
    		•  1.86366637427031 bayes_pls_golite062009
  • protein binding
    		•  1.52285169518311 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.797357482444881 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.157803422287271 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle