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Protein Overview: m4-PA

General Information:
Name(s) found: m4-PA / FBpp0084353 [FlyBase]
Description(s) found:
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  • pir||S03630 neurogenic gene complex E(spl) protein m4 - fruit fly (Drosophila melanogaster) [NCBI NR]
  • gi|7950|emb|CAA34551.1| unnamed protein product [Drosophila melanogaster] [NCBI NR]
  • gi|7301425|gb|AAF56551.1| E(spl) region transcript m4 [Drosophila melanogaster] [NCBI NR]
  • gi|55715443|gb|AAV59235.1| enhancer of split m4 protein [Drosophila melanogaster] [NCBI NR]
  • gi|55715430|gb|AAV59223.1| enhancer of split m4 protein [Drosophila melanogaster] [NCBI NR]
  • gi|55715417|gb|AAV59211.1| enhancer of split m4 protein [Drosophila melanogaster] [NCBI NR]
  • gi|55715404|gb|AAV59199.1| enhancer of split m4 protein [Drosophila melanogaster] [NCBI NR]
  • gi|55715378|gb|AAV59175.1| enhancer of split m4 protein [Drosophila melanogaster] [NCBI NR]
  • gi|55715365|gb|AAV59163.1| enhancer of split m4 protein [Drosophila melanogaster] [NCBI NR]
  • gi|55715339|gb|AAV59139.1| enhancer of split m4 protein [Drosophila melanogaster] [NCBI NR]
  • gi|55715326|gb|AAV59127.1| enhancer of split m4 protein [Drosophila melanogaster] [NCBI NR]
  • gi|55715313|gb|AAV59115.1| enhancer of split m4 protein [Drosophila melanogaster] [NCBI NR]
  • gi|55715300|gb|AAV59103.1| enhancer of split m4 protein [Drosophila melanogaster] [NCBI NR]
  • gi|55715287|gb|AAV59091.1| enhancer of split m4 protein [Drosophila melanogaster] [NCBI NR]
  • gi|55715274|gb|AAV59079.1| enhancer of split m4 protein [Drosophila melanogaster] [NCBI NR]
  • gi|55715261|gb|AAV59067.1| enhancer of split m4 protein [Drosophila melanogaster] [NCBI NR]
  • gi|55715248|gb|AAV59055.1| enhancer of split m4 protein [Drosophila melanogaster] [NCBI NR]
  • gi|17738209|ref|NP_524510.1| E(spl) region transcript m4 [Drosophila melanogaster] [NCBI NR]
  • gi|119570|sp|P13095.1|ESM4_DROME RecName: Full=Enhancer of split m4 protein; Short=E(spl)m4 [NCBI NR]
  • Enhancer of split m4 protein OS=Drosophila melanogaster GN=m4 PE=2 SV=1 [Swiss-Prot]
  • The gene E(spl) region transcript m4 is referred to in FlyBase by the symbol Dmel\m4 (CG6099, FBgn0002629). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:21849757..21850215. It has the cytological map location 96F10. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: sensory organ development; Notch signaling pathway; cell fate specification. 13 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: peripheral nervous system; nervous system; adult segment; adult mesothoracic segment; organ system; external compound sense organ; compound cell cluster organ; central nervous system; integumentary plate; wing margin bristle. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG6099-PA translation from_gene[CG6099 m4 FBgn0002629] seq_release:3 mol_weight=17250 cds_boundaries:(3R:21,839,125..21,839,580[-]) aa_length:152 transcript_info:[CG6099-RA seq_release:3] gene_info:[gene symbol:m4 FBgn0002629 gene_boundaries:(3R:21,83 [hmr_yeast5_DM3-1_pombe.fasta]
  • (P13095) Enhancer of split m4 protein (E(spl)m4) [DrosMelano7227.FASTAC.txt]
  • (AE003754) m4 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG6099-PA [Drosophila melanogaster]gi|17738209|ref|NP_524510.1| CG6099-PA [Drosophila melanogaster]gi|85072|pir||S03630 neurogenic gene complex E(spl) protein m4 - fruit fly (Drosophila melanogaster)gi|7950|emb|CAA34551.1| unnamed protein product [Dro [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:complement(21849757..21850215); ID=FBpp0084353; name=m4-PA; parent=FBgn0002629,FBtr0084980; dbxref=FlyBase:FBpp0084353,FlyBase_Annotation_IDs:CG6099-PA,GB_protein:AAF56551.1,REFSEQ:NP_524510,GB_protein:AAF56551; MD5=ccd364e2ab31f336ac [fly-100309-contam.fasta]
  • enhancer of split m4 protein [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Enhancer of split m4 protein (E(spl)m4) [nr-271106-contam.fasta]
  • E(spl) region transcript m4 CG6099-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • unnamed protein product [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG6099-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:complement(21849757..21850215); ID=FBpp0084353; name=m4-PA; parent=FBgn0002629,FBtr0084980; dbxref=FlyBase:FBpp0084353,FlyBase_Annotation_IDs:CG6099-PA,GB_protein:AAF56551.1,REFSEQ:NP_524510,GB_protein:AAF56551; MD5=ccd364e2ab31f336ac0dda1945e73d1e; length=152; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:complement(21849757..21850215); ID=FBpp0084353; name=m4-PA; parent=FBgn0002629,FBtr0084980; dbxref=FlyBase:FBpp0084353,FlyBase_Annotation_IDs:CG6099-PA,GB_protein:AAF56551.1,REFSEQ:NP_524510,GB_protein:AAF56551; MD5=ccd364e2ab31f336ac0dda1945e73d1e; length=152; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Enhancer of split m4 protein OS=Drosophila melanogaster GN=m4 PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3R:complement(21849757..21850215); ID=FBpp0084353; name=m4-PA; parent=FBgn0002629,FBtr0084980; dbxref=FlyBase:FBpp0084353,FlyBase_Annotation_IDs:CG6099-PA,GB_protein:AAF56551.1,REFSEQ:NP_524510,GB_protein:AAF56551,FlyMine:FBpp0084353,modMine:FBpp0084353; MD5=ccd364e2ab31f336ac0dda1945e73d1e; length=152; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:complement(26024035..26024493); ID=FBpp0084353; name=E(spl)m4-BFM-PA; parent=FBgn0002629,FBtr0084980; dbxref=FlyBase:FBpp0084353,FlyBase_Annotation_IDs:CG6099-PA,GB_protein:AAF56551.1,REFSEQ:NP_524510,GB_protein:AAF56551,FlyMine:FBpp0084353,modMine:FBpp0084353; MD5=ccd364e2ab31f336ac0dda1945e73d1e; length=152; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:complement(26024035..26024493); ID=FBpp0084353; name=E(spl)m4-BFM-PA; parent=FBgn0002629,FBtr0084980; dbxref=FlyBase:FBpp0084353,FlyBase_Annotation_IDs:CG6099-PA,GB_protein:AAF56551.1,REFSEQ:NP_524510,GB_protein:AAF56551,FlyMine:FBpp0084353,modMine:FBpp0084353; MD5=ccd364e2ab31f336ac0dda1945e73d1e; length=152; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0084353 type=protein; loc=3R:complement(26024035..26024493); ID=FBpp0084353; name=E(spl)m4-BFM-PA; parent=FBgn0002629,FBtr0084980; dbxref=FlyBase:FBpp0084353,FlyBase_Annotation_IDs:CG6099-PA,GB_protein:AAF56551.1,REFSEQ:NP_524510,GB_protein:AAF56551,FlyMine:FBpp0084353,modMine:FBpp0084353; MD5=ccd364e2ab31f336ac0dda1945e73d1e; length=152; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3R:complement(26024035..26024493); ID=FBpp0084353; name=E(spl)m4-BFM-PA; parent=FBgn0002629,FBtr0084980; dbxref=FlyBase:FBpp0084353,FlyBase_Annotation_IDs:CG6099-PA,GB_protein:AAF56551.1,REFSEQ:NP_524510,GB_protein:AAF56551,UniProt/Swiss-Prot:P13095,FlyMine:FBpp0084353,modMine:FBpp0084353; MD5=ccd364e2ab31f336ac0dda1945e73d1e; length=152; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 152 amino acids

    Gene Ontology:
    Cellular Component: nucleus [TAS]
    Biological Process: Notch signaling pathway [IMP][NAS]
    cell fate specification [IMP]
    sensory organ development [IMP]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCQNKINTNN TMTIKSNKKL SYSVKKLLQK IFKQQQRVEE EQNLKNALKA NSLESLESME  60
   61 NSRNADLESA SICASLESCE NEANERLSQS CEIEDYDFEQ LPTVPVHFVR TAHGTFFWTA 120
  121 VSDLPADNDL VEPLYCSTSN AIAIPQDRWV QA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..152] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle