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Protein Overview: Lgr3-PA

General Information:
Name(s) found: Lgr3-PA / FBpp0084273 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • The gene Lgr3 is referred to in FlyBase by the symbol Dmel\Lgr3 (CG31096, FBgn0039354). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:21491531..21502938. It has the cytological map location 96E8-96E9. Based on sequence similarity, it is predicted to have molecular function</span>: protein-hormone receptor activity; neuropeptide receptor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: G-protein coupled receptor protein signaling pathway. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 765 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEA][ISS]
    Biological Process: G-protein coupled receptor protein signaling pathway [IEA][ISS]
    Molecular Function: G-protein coupled receptor activity [IEA][NAS]
    protein binding [IEA]
    neuropeptide receptor activity [ISS]
    protein-hormone receptor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVYGRSIAVG FCLMTVVLLL AAVIFYLSLG PCPAASFACD NGTLCVPRRQ MCDSRNDCAD  60
   61 SSDENPVECG LLYGSKEIAD KIVRNAIEKK QQRLISAVSN ASGADSTTSM VPRNQSLTLN 120
  121 MTCDIVTYPK ACQCGQGTIL YCGRYAKLRR FPRLSSEVTN LIIIRNNLTL RDNIFANFTR 180
  181 LQKLTLKYNN ISRVPLGSFS GLFHLERLEL SHNNVSHLPH GVFLGLHSLQ WLFLVNNHLH 240
  241 HLPVEQLRFF RRLEWLVLSR NRLTLRNVQL PKIPTLYEVY LDFNRIEYIG EETFSQLDNL 300
  301 HLLDLQHNLI THIHGRAFAN LTNMRDIRLV GNPIKELSGE TFLHNTRLEA LSLALMPIHI 360
  361 SSSLMEPLNI SFLNLTGIRY DHIDFEAINS MRNLTYIIYD RFFYCSMTPR VRMCKPSTDG 420
  421 VSSFQDLLSK PVLRYSAWVM ATLTIAGNVL VLWGRFIYRD ENVAVTMVIR NLALADMLMG 480
  481 FYLVTIGVQD YRYRNEYYKV VLDWITSWQC TLIGTLAVSS SEVSMLILAF MSLERFLLIA 540
  541 DPFRGHRSIG NRVMWLALIC IWITGVGLAV APVLLWRTST LPYYGSYSGT CFPLHIHEAF 600
  601 PMGWLYSAFV FLGVNLLLLV MIAMLYTALL ISIWRTRSAT PLTLLDCEFA VRFFFIVLTD 660
  661 FLCWVPIIVM KIWVFFNYNI SDDIYAWLVV FVLPLNSAVN PLLYTFTTPK YRNQIFLRGW 720
  721 KKITSRKRAE AGNGNVATTT TGTATGSSQH PDDFTIFAKA AMRCH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..415] PSI-BLAST 47.0 No description for 2id5A was found.
    2 View Details [416..765] PSI-BLAST 41.69897 Rhodopsin


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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