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Protein Overview: FBpp0307940, Trf...

General Information:
Name(s) found: FBpp0307940 [FlyBase]
Trf4-2-PA / FBpp0084094 [FlyBase]
Description(s) found:
Found 25 descriptions.
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  • type=protein; loc=3R:20751293..20752516; ID=FBpp0307940; name=Trf4-2-PB; parent=FBgn0039251,FBtr0337011; dbxref=REFSEQ:NP_001262941,GB_protein:AGB96321,FlyBase:FBpp0307940,FlyBase_Annotation_IDs:CG17462-PB; MD5=c22eb4d7e3f2c86eb236ae75bd5b2685; length=407; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\Trf4-2 (CG17462, FBgn0039251). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:20750938..20752576. It has the cytological map location 96B9. Based on sequence similarity, it is predicted to have molecular function</span>: DNA-directed DNA polymerase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: sister chromatid cohesion. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 407 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISS]
    Biological Process: sister chromatid cohesion [ISS][NAS]
    Molecular Function: DNA-directed DNA polymerase activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCDEANPAKP WQLPDVVYGN GIPALCLLHQ EIEQFYNYIR STPTEFCLRA GAVRRIEDVV  60
   61 LSIWPSASVD LFGSFRTGLN LPDSDIDLVV YYKFWNPRLL HELQNELVSQ GVTDPDTVTV 120
  121 LDKASVPVVK FTDLISRIRF DVTFNSVASG VQAADLIKDF IRHFPELPKL VMVLKQFLSL 180
  181 HGFNEVYNSG GVSSYALTLM VISFLQQHAR SNRRLSEHSK LALLLIQFLD YYGRKFDFFK 240
  241 YGISVLGQGG CVEKARLRST LGENNWQSVL CIEDPVTPTN DIGRSSYGVL GVMQGFGAAF 300
  301 VKLSKLVDSD SSKIVGPILA NIVEVPQSII NYRAWVHYNF QHLLTPELPC ADSLVQPSPT 360
  361 GSTSPSASAS ASEDERSGGP ATIGFGRCDD PPQNIDIVAD LANLKMN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..407] PSI-BLAST 73.69897 Crystal structure of poly(A) polymerase in complex with 3'-dATP and magnesium chloride

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.33304794312594 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.827216703196783 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.782538534425072 bayes_pls_golite062009
  • protein binding
    		•  0.325334122978198 bayes_pls_golite062009
  • transferase activity
    		•  0.212392916986958 bayes_pls_golite062009
  • catalytic activity
    		•  0.209725173901451 bayes_pls_golite062009
  • transcription factor binding
    		•  0.136601293399466 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.79

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle