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Protein Overview: CG31148-PA

General Information:
Name(s) found: CG31148-PA / FBpp0083833 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG31148 (CG31148, FBgn0051148). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:19526360..19528324. It has the cytological map location 95A8. Based on sequence similarity, it is predicted to have molecular function</span>: glucosylceramidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: lysosome organization; sphingolipid metabolic process; carbohydrate metabolic process. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 561 amino acids

    Gene Ontology:
    Cellular Component: lysosome [IEA]
    Biological Process: lysosome organization [IEA]
    carbohydrate metabolic process [IEA]
    sphingolipid metabolic process [IEA]
    Molecular Function: glucosylceramidase activity [ISS]
    cation binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKMFASRGM LVLGVLLVSA IGGQSESIPC KLIDAEHGKV CVCTADYCDY LENPVLTDEN  60
   61 EWFLISSSKQ GLRFSTTSDK FGKEEKFTVQ DYVEPTQETA NATILSRLLD KVVDSAFTLE 120
  121 SRESSITRTV TLRLDRSKTH QKMVGFGGSY TGAVEYLVEN FKHSELADHL YKSFYAEDGL 180
  181 GFNLMRVSIG GCDFDLEPWS YAEEEGDTEL SDMDELNAHD VTRVAQIKRL IEVSGVKNLL 240
  241 VKGAAWSSPP WMKTNNRWTG FGRLKRAYYQ TWADYHLRWL RLMKDNGIPI WAISTGNEPL 300
  301 NGIIFMYFVK FMSLGWTPQT QAIWLNDYLG PTIRNSEFKD ITLFGNDDQR YSFPHWFKMM 360
  361 NRTRPNSIDY LDGLSLHWYW DEIFGNSFIE QTKEYAPDKI LIVSESCIGD KPWQAAAPLL 420
  421 GSWERAEKYA RDYLLNIKLG FHGWIDWNIC LDEIGGPNYV DNTVDAPVIV NTTTFEEFYK 480
  481 QPMFYAIGHF SKWVPEGSVR IDAVPSNVNL DSVAFLRPDN KITAVLFNSG RADLDITLVD 540
  541 SIRGQFVVNV PAKSIHTLLY S

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..561] PSI-BLAST 150.0 No description for 2v3dA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity, hydrolyzing O-glycosyl compounds
    		•  4.11319792356479 bayes_pls_golite062009
  • hydrolase activity, acting on glycosyl bonds
    		•  3.92012282533754 bayes_pls_golite062009
  • chitinase activity
    		•  2.45357334610104 bayes_pls_golite062009
  • catalytic activity
    		•  1.85569074294201 bayes_pls_golite062009
  • hydrolase activity
    		•  1.54366929433155 bayes_pls_golite062009
  • amylase activity
    		•  0.748967897302847 bayes_pls_golite062009
  • glucosidase activity
    		•  0.528679164808812 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.4998423581103 bayes_pls_golite062009
  • hexosaminidase activity
    		•  0.423006654245821 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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