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Protein Overview: eIF-3p66-PB

General Information:
Name(s) found: eIF-3p66-PB / FBpp0088565 [FlyBase]
Description(s) found:
Found 23 descriptions.
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  • The gene Eukaryotic initiation factor 3 p66 subunit is referred to in FlyBase by the symbol Dmel\eIF-3p66 (CG10161, FBgn0040227). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:19505767..19508049. It has the cytological map location 95A7. Based on sequence similarity, it is predicted to have molecular function</span>: translation initiation factor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: translational initiation. 3 alleles are reported. The phenotype of these alleles is annotated with: eye. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 560 amino acids

    Gene Ontology:
    Cellular Component: cytosol [ISS][NAS]
    eukaryotic translation initiation factor 3 complex [ISS][NAS]
    Biological Process: translational initiation [IEA][ISS][NAS]
    translation [NAS]
    Molecular Function: translation initiation factor activity [IEA][ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSETINTAAQ FPSFEKPTVQ FNEKGWGPCE LPDTFKDVPY QPFSKNDRLG KICDWTNTSN  60
   61 NDKKYQNKYA SSFGTGIQYS YYHEEDETTF HLVDTARVQK PPHQRGRFRN MRNSRSGRGR 120
  121 NARGGLNTHG MTTLSGKNVK ARDPRHGRGM GKKFGHRGPP PKMRESSVAV RADWASIEEM 180
  181 DFPRLIKLSL PNIKEGVDIV TCGTLEYYDK TYDRINVKNE KPLQKIDRIV HTVTTTDDPV 240
  241 IRRLSKTVGN VFATDAILAT IMCSTRSNYS WDIVIEKVGD KVFMDKRDHT EFDLLTVNES 300
  301 SVEPPTDDDS SCNSPRNLAI EATFINHNFS QQVLKTGDQE PKYKFEESNP FISEDEDIQV 360
  361 ASVGYRYKKW ELGSDIVLVA RCEHDGVLQT PSGEPQFMTI KALNEWDSKL ANGVEWRQKL 420
  421 DTQRGAVLAN ELRNNACKLA KWTVQAVLAG SDQLKLGYVS RINPRDHSRH VILGTQQFKP 480
  481 HEFATQINLS MDNAWGILRC IIDLVMKQKD GKYLIMKDPN KPIIRLYDIP DNTFDSDDSD 540
  541 DGEGDDEGFQ QVYNYAHNKI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..64] MSA 1.03199 View MSA. No confident structure predictions are available.
    2 View Details [65..268] deduced N/A No confident structure predictions are available.
    3 View Details [269..372] deduced N/A No confident structure predictions are available.
    4 View Details [373..462] deduced N/A No confident structure predictions are available.
    5 View Details [463..560] MSA 2.030965 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

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