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Protein Overview: CG10184-PA

General Information:
Name(s) found: CG10184-PA / FBpp0083872 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG10184 (CG10184, FBgn0039094). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:19428229..19431209. It has the cytological map location 95A4. Based on sequence similarity, it is predicted to have molecular function</span>: threonine aldolase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: cellular amino acid metabolic process. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 383 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: cellular amino acid metabolic process [IEA]
    Molecular Function: pyridoxal phosphate binding [IEA]
    threonine aldolase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTHSVVDLR SDTVSQPTDK MRARMATAVV GDDVYGEDPT VNELEARTAA IFGKEAGLFV  60
   61 PSGTMGNLLA IMVHCHRRGT EALVGDLSHI FLYEQGGASH LAGVQLATLK NEQDGTFSLQ 120
  121 DLRRRIRHED CHEPITSLVV VEQTHNICGG KVVPLAFLDE LAALVRQPGV GTGNARIALH 180
  181 MDGARVFNAA TALGVGVERI CRDFDSVSIC LSKGLSAPVG SVLVGSKAFI SEAHRLRKAL 240
  241 GGGMRQVGVL AAAGLVALDE VVPLLSKDHE RTNKIANAIY ELKSPNITVH VSSVQSNILL 300
  301 VEITQPKLTA SEFSTRLSIV DAGEVEAGVK DKNGAGIVVK ASARDWAFAR LVLYHQVDDE 360
  361 QVDLAIRKLK YVIGQYDKQF PRT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..383] PSI-BLAST 63.69897 Crystal structure of L-ALLO-threonine aldolase (tm1744) from Thermotoga maritima at 2.25 A resolution

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  2.29878871754893 bayes_pls_golite062009
  • glycine dehydrogenase (decarboxylating) activity
    		•  1.97244784321411 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor
    		•  1.97244784321411 bayes_pls_golite062009
  • threonine aldolase activity
    		•  1.80396420390785 bayes_pls_golite062009
  • transferase activity, transferring nitrogenous groups
    		•  1.28316822767388 bayes_pls_golite062009
  • L-aspartate:2-oxoglutarate aminotransferase activity
    		•  1.27059944776392 bayes_pls_golite062009
  • transaminase activity
    		•  1.24990480711889 bayes_pls_golite062009
  • O-phospho-L-serine:2-oxoglutarate aminotransferase activity
    		•  0.994935084630764 bayes_pls_golite062009
  • transferase activity
    		•  0.737426388870721 bayes_pls_golite062009
  • glycine hydroxymethyltransferase activity
    		•  0.271623203801431 bayes_pls_golite062009
  • glycine C-acetyltransferase activity
    		•  0.154736911817138 bayes_pls_golite062009
  • carbon-carbon lyase activity
    		•  0.11598778799668 bayes_pls_golite062009
  • methyltransferase activity
    		•  0.093175965161657 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  0.0150995688991599 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.89

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle