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Protein Overview: EloA-PA

General Information:
Name(s) found: EloA-PA / FBpp0083766 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene Elongin A is referred to in FlyBase by the symbol Dmel\EloA (CG6755, FBgn0039066). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:19077266..19080793. It has the cytological map location 94E9. There is experimental evidence that it has the molecular function</span>: positive transcription elongation factor activity; RNA polymerase II transcription elongation factor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: RNA elongation from RNA polymerase II promoter. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 643 amino acids

    Gene Ontology:
    Cellular Component: transcription elongation factor complex [ISS]
    integral to membrane [IEA]
    Biological Process: transcription [IEA]
    regulation of transcription [IEA]
    RNA elongation from RNA polymerase II promoter [ISS]
    Molecular Function: DNA binding [IEA]
    transcription elongation regulator activity [ISS]
    RNA polymerase II transcription elongation factor activity [IDA][ISS]
    protein binding [IEA]
    positive transcription elongation factor activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASTSNLLDV VRHYQRSIEK HGEDEQRLLH CITKLFNLPI KFEHLQETGI GKTVNALRKI  60
   61 SGEVGVAAKT LVTKWKAMVA KEDPSIASTP TAIHNEEDSG KTKSSDEDPD QENKGGNSSS 120
  121 GEDLNTSKHK SKHAKSTKHE RSSSSRSHSK SRSDSDKKHK SSRHDKSKDR DKDREGQKEA 180
  181 KEHKEKKSNG EHKSKDSSKS SSSHKSSKSE SHKSEHTKSK HEKDKTSHSE LKEVKDKSSK 240
  241 HKSSSSKSSK RSHSPPRHEE ESQKAKIPKV KSKSEEDSAD GFDSSMGANF DDVLGLLNIP 300
  301 ISSKKSSSNS KSKFVAKPTA APSSSALSAP TTAGSSKEAL STSSRPTSKK PELLASTAKL 360
  361 EPLDPNIALE LPTISNNYKP MPLNQTVMDV VFNQGGSHKA QASRYFNESE ALAQGISSKT 420
  421 MRTKIYSGVR TGQILQVPSL FDLCTRVLQK NIDALEYTGG VPFEVLRPVL ERATPQQLLN 480
  481 FEEYNPYLMD DSDVLWQQHV QRHCRSQRRE EMETWREMFL RCQEEKDRKL SILAESIKAS 540
  541 QKISEAPVRK TQLAFVDSMV KPPRSVQRKQ EQYGTKGKLI ATPAARVAAL SSVTPNAAKV 600
  601 GDARLRVLAA ARDTAQVGAG PARSKKAPLM AKTLQFMRGR LKR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..176] FFAS03 2.46 RNA polymerase II-TFIIS complex
    2 View Details [177..420] deduced N/A No confident structure predictions are available.
    3 View Details [421..559] Pfam 81.853872 No description for PF06881.2 was found. No confident structure predictions are available.
    4 View Details [560..643] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle