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Protein Overview: cenB1A-PB

General Information:
Name(s) found: cenB1A-PB / FBpp0083762 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene centaurin beta 1A is referred to in FlyBase by the symbol Dmel\cenB1A (CG6742, FBgn0039056). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:18944125..18949941. It has the cytological map location 94E1. Based on sequence similarity, it is predicted to have molecular function</span>: ARF GTPase activator activity. There is experimental evidence that it is involved in the biological process</span>: phagocytosis, engulfment. 2 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 598 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: phagocytosis, engulfment [IMP]
    regulation of ARF GTPase activity [IEA]
    Molecular Function: zinc ion binding [IEA]
    ARF GTPase activator activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQNRHMSVNR YCDSNTNSTS NKIEGYLFKK KSKGFKTWCR RWFYLSDNQL VYSDLDSHCR  60
   61 KRSNEDSFSV MEEDLRICSV RPVNEGDRRF CFEVISPTKS HILQADSADM LSLWISALQH 120
  121 SIGAAIQHDS THHSRPQSTN APNNSLPAKR RIHWEEFLKI PGNAYCCDCR SPEPRWASIN 180
  181 LGITLCIECS GVHRSLGVHY SKVRSLTLDA WESENVKVMM ELGNEVVNRI YEARIGDDCG 240
  241 LKKPTEQCEI GVREAWIKAK YVERRFVCGM PKPQELLASE TAEVLSIDSG GVVEDGESGG 300
  301 SGIAKRATLS LGGTRKWAVK KLRRRQKQRS IPKTLSDDPS IYNTAKTGDE LEDDDDDESI 360
  361 NIPSMSLSIS RDDLLVIGDD LALDRLETPG ILGSDQESTD GESDAESPEE LPFSQLDANQ 420
  421 LLYMASVVHN LPVMCMAFAL GADKMWKNPQ DRQRSFLHQA VISGSVMACE FLLLNGAAID 480
  481 AVDEMGYSAL HISTAKGHIA QVYLLLKHKA AYDLSSSDGK KALDIAVDQE NADIVTLLRL 540
  541 TQLNDEIGPN DEYNGEDETY KNVMKDFSKL PASQTRVLRQ RHDSNTLESQ RSSLTNSD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..141] PSI-BLAST 20.69897 No description for 2yryA was found.
    2 View Details [142..241] PSI-BLAST 22.69897 Pyk2-associated protein beta; Pyk2-associated protein beta ARF-GAP domain
    3 View Details [242..598] PSI-BLAST 78.221849 Ankyrin-R

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • protein binding
    		•  1.13763770131654 bayes_pls_golite062009
  • binding
    		•  1.12166073582532 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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