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Protein Overview: Dph5-PA

General Information:
Name(s) found: Dph5-PA / FBpp0083673 [FlyBase]
Description(s) found:
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  • gi|5679126|gb|AAD46869.1|AF160929_1 BcDNA.LD12153 [Drosophila melanogaster] [NCBI NR]
  • gi|28572120|ref|NP_524452.4| diphthamide methyltransferase [Drosophila melanogaster] [NCBI NR]
  • gi|28381425|gb|AAN13913.2| diphthamide methyltransferase [Drosophila melanogaster] [NCBI NR]
  • The gene Diphthamide methyltransferase is referred to in FlyBase by the symbol Dmel\Dph5 (CG31289, FBgn0024558). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:18407749..18408950. It has the cytological map location 94B5. Based on sequence similarity, it is predicted to have molecular function</span>: diphthine synthase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: peptidyl-diphthamide biosynthetic process from peptidyl-histidine. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG31289-PA translation from_gene[CG31289 Dph5 FBgn0024558] seq_release:3 mol_weight=31620 cds_boundaries:(3R:18,398,586..18,399,498[-]) aa_length:281 transcript_info:[CG31289-RA seq_release:3] gene_info:[gene symbol:Dph5 synonyms:[CG5275] FBgn0024558 [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q8IN02) CG31289-PA [DrosMelano7227.FASTAC.txt]
  • CG31289-PA [Drosophila melanogaster]gi|28572120|ref|NP_524452.4| CG31289-PA [Drosophila melanogaster]gi|5679126|gb|AAD46869.1| BcDNA.LD12153 [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:complement(18407927..18408637,18408708..18408842); ID=FBpp0083673; name=Dph5-PA; parent=FBgn0024558,FBtr0084280; dbxref=FlyBase:FBpp0083673,FlyBase_Annotation_IDs:CG31289-PA,GB_protein:AAN13913.2,REFSEQ:NP_524452,GB_protein:AAN13913; [fly-100309-contam.fasta]
  • Diphthamide methyltransferase CG31289-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG31289-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • BcDNA.LD12153 [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:complement(18407927..18408637,18408708..18408842); ID=FBpp0083673; name=Dph5-PA; parent=FBgn0024558,FBtr0084280; dbxref=FlyBase:FBpp0083673,FlyBase_Annotation_IDs:CG31289-PA,GB_protein:AAN13913.2,REFSEQ:NP_524452,GB_protein:AAN13913; MD5=cfcb37e503aa52dc8ba0cba7b8c17df8; length=281; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:complement(18407927..18408637,18408708..18408842); ID=FBpp0083673; name=Dph5-PA; parent=FBgn0024558,FBtr0084280; dbxref=FlyBase:FBpp0083673,FlyBase_Annotation_IDs:CG31289-PA,GB_protein:AAN13913.2,REFSEQ:NP_524452,GB_protein:AAN13913; MD5=cfcb37e503aa52dc8ba0cba7b8c17df8; length=281; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • BcDNA.LD12153 OS=Drosophila melanogaster GN=Dph5 PE=2 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3R:complement(18407927..18408637,18408708..18408842); ID=FBpp0083673; name=Dph5-PA; parent=FBgn0024558,FBtr0084280; dbxref=FlyBase:FBpp0083673,FlyBase_Annotation_IDs:CG31289-PA,GB_protein:AAN13913.2,REFSEQ:NP_524452,GB_protein:AAN13913,FlyMine:FBpp0083673,modMine:FBpp0083673; MD5=cfcb37e503aa52dc8ba0cba7b8c17df8; length=281; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:complement(join(22582986..22583120,22582205..22582915)); ID=FBpp0083673; name=Dph5-PA; parent=FBgn0024558,FBtr0084280; dbxref=FlyBase:FBpp0083673,FlyBase_Annotation_IDs:CG31289-PA,GB_protein:AAN13913.2,REFSEQ:NP_524452,GB_protein:AAN13913,FlyMine:FBpp0083673,modMine:FBpp0083673; MD5=cfcb37e503aa52dc8ba0cba7b8c17df8; length=281; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:complement(join(22582986..22583120,22582205..22582915)); ID=FBpp0083673; name=Dph5-PA; parent=FBgn0024558,FBtr0084280; dbxref=FlyBase:FBpp0083673,FlyBase_Annotation_IDs:CG31289-PA,GB_protein:AAN13913.2,REFSEQ:NP_524452,GB_protein:AAN13913,FlyMine:FBpp0083673,modMine:FBpp0083673; MD5=cfcb37e503aa52dc8ba0cba7b8c17df8; length=281; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of Q9VCY2, BcDNA.LD12153 OS=Drosophila melanogaster GN=Dph5 PE=1 SV=2 [DROME.fasta.20160308]
  • FBpp0083673 type=protein; loc=3R:complement(join(22582986..22583120,22582205..22582915)); ID=FBpp0083673; name=Dph5-PA; parent=FBgn0024558,FBtr0084280; dbxref=FlyBase:FBpp0083673,FlyBase_Annotation_IDs:CG31289-PA,GB_protein:AAN13913.2,REFSEQ:NP_524452,GB_protein:AAN13913,FlyMine:FBpp0083673,modMine:FBpp0083673; MD5=cfcb37e503aa52dc8ba0cba7b8c17df8; length=281; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3R:complement(join(22582986..22583120,22582205..22582915)); ID=FBpp0083673; name=Dph5-PA; parent=FBgn0024558,FBtr0084280; dbxref=FlyBase:FBpp0083673,FlyBase_Annotation_IDs:CG31289-PA,GB_protein:AAN13913.2,REFSEQ:NP_524452,GB_protein:AAN13913,UniProt/TrEMBL:Q8IN02,FlyMine:FBpp0083673,modMine:FBpp0083673; MD5=cfcb37e503aa52dc8ba0cba7b8c17df8; length=281; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 281 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: peptidyl-diphthamide biosynthetic process from peptidyl-histidine [ISS]
    Molecular Function: diphthine synthase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFYLIGLGLG DLKDITVKGL EIVKQCSRVY LEMYTSILGC SLEDMQEFYG RPLLLADRDL  60
   61 VEQGADEILA GAGESDVALL VVGDPFGATT HTDFILRAKE KNIPYKVIHN ASIMNAVGCC 120
  121 GLQLYKFGET VSIPYWDETW KPDSFYDKIK LNRLHNMHTL CLLDIKVKEP TPESLMRKRK 180
  181 EYMPPRFMTV AEAAHQLLSI VEKKDSLEKN TVLNEQSLCV GLARVGQESQ QIAVGTLLEM 240
  241 RSTDLGGPLH SLIIPAKEMH PLEVEFLQQY APSIKLDDYN H

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..281] PSI-BLAST 39.0 No description for 2dv4A was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
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