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The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones. The chemical reactions and pathways involving peptidyl-diphthamide, a modified histidine residue. The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. The chemical reactions and pathways by which individual cells transform chemical substances. The modification of peptidyl-histidine. The posttranslational modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor eEF-2.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: peptidyl-diphthamide biosynthetic process from peptidyl-histidine
Acc: GO:0017183
Aspect: Biological Process
Desc: The posttranslational modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor eEF-2.
Synonyms:
  • peptidyl-diphthamide synthesis from peptidyl-histidine
  • peptidyl-diphthamide anabolism from peptidyl-histidine
  • peptidyl-diphthamide formation from peptidyl-histidine
Proteins in PDR annotated with:
   This term: 24 [Search]
   Term or descendants: 24 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0017183 - peptidyl-diphthamide biosynthetic process from peptidyl-histidine (interactive image map)
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