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Protein Overview: CG33092-PG

General Information:
Name(s) found: CG33092-PG / FBpp0083544 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG33092 (CG33092, FBgn0053092). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:17703658..17706418. It has the cytological map location 93F14. Based on sequence similarity, it is predicted to have molecular function</span>: 1-pyrroline-5-carboxylate dehydrogenase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: glutamate biosynthetic process; proline catabolic process. One allele is reported. No phenotypic data is available. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 608 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial matrix [ISS]
    Biological Process: glutamate biosynthetic process [ISS]
    oxidation reduction [IEA]
    proline catabolic process [ISS]
    Molecular Function: 1-pyrroline-5-carboxylate dehydrogenase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMSKVAHGIV SNMRSILPRL EASVKGGTSK RPELSEHFTL DEMVANEKLL QYDEGSKERT  60
   61 ELETALLGVL NRVEHVPIVI NGQEFQAKED FQQVLPYDIQ QPIAHYGHAH RVLIQMAIDK 120
  121 SVEAQVKWDK VRLSDRIDIW ERAAMLIAGR YRYNIIAATM LGQGKTLRQA EMDVAELVDF 180
  181 MRINPVFLRE LANYEPIRDI QNNCRNSMRL RGLSGFVAAI SPFNFTGIAA NLAYTPALMG 240
  241 NSVIWKPSDS AILSNYFVFK ALREAGVPDG VVNFVPAEET TFASVVTQHP KLAGINFTGT 300
  301 STVLKVLWQL VAQNINFYQN YPRLVGEGGG KNFHFVHSSA EPETAVACTI RAAFEYAGQK 360
  361 CSSCSMLYVP ESLWQNHIRE PLLEITASLV VRQDATYCDS FCSAVINRRA YDRIYMWLRY 420
  421 IDQSPSCQIL VGGSCDKRRG YYVDPTVVLV KDLDNIICRE ELLAPILGVY VYPDHKLKET 480
  481 MEKVAQINHG LTGSVFAQDQ NFIEEAYDAF RVNVGNLNVN DKSTGLMVGQ QPFGAGHMTG 540
  541 TSDKLGTPHS LLRWTSPQVI KESYKTHRNI FYPYMQINDQ EQGIAQSDMV SQDESSFGHF 600
  601 NSDGNKVV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..608] PSI-BLAST 161.0 Aldehyde reductase (dehydrogenase), ALDH

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  5.09598561374689 bayes_pls_golite062009
  • oxidoreductase activity
    		•  4.47226217021998 bayes_pls_golite062009
  • 1-pyrroline-5-carboxylate dehydrogenase activity
    		•  4.35175408702761 bayes_pls_golite062009
  • malonate-semialdehyde dehydrogenase (acetylating) activity
    		•  4.2273960318884 bayes_pls_golite062009
  • methylmalonate-semialdehyde dehydrogenase (acylating) activity
    		•  3.87605237828483 bayes_pls_golite062009
  • succinate-semialdehyde dehydrogenase [NAD(P)+] activity
    		•  3.64672165191647 bayes_pls_golite062009
  • 3-chloroallyl aldehyde dehydrogenase activity
    		•  3.37049090049734 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
    		•  3.2867555127991 bayes_pls_golite062009
  • glutamate-5-semialdehyde dehydrogenase activity
    		•  3.27180265380824 bayes_pls_golite062009
  • aldehyde dehydrogenase (NAD) activity
    		•  2.81851373615334 bayes_pls_golite062009
  • catalytic activity
    		•  2.80804701752928 bayes_pls_golite062009
  • succinate-semialdehyde dehydrogenase activity
    		•  2.71501590413507 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH group of donors
    		•  2.70230501280821 bayes_pls_golite062009
  • aldehyde dehydrogenase [NAD(P)+] activity
    		•  2.43250909158896 bayes_pls_golite062009
  • aminobutyraldehyde dehydrogenase activity
    		•  2.35958138496479 bayes_pls_golite062009
  • acyl-CoA binding
    		•  2.26220696569489 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor
    		•  1.6559690223037 bayes_pls_golite062009
  • retinal dehydrogenase activity
    		•  1.42867174920845 bayes_pls_golite062009
  • binding
    		•  0.868255071997355 bayes_pls_golite062009
  • retinoid binding
    		•  0.801468424891608 bayes_pls_golite062009
  • isoprenoid binding
    		•  0.719034630339067 bayes_pls_golite062009
  • benzaldehyde dehydrogenase activity
    		•  0.38785102096584 bayes_pls_golite062009
  • histidinol dehydrogenase activity
    		•  0.258030369394064 bayes_pls_golite062009
  • benzaldehyde dehydrogenase (NAD+) activity
    		•  0.23487570676521 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.61

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle