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Protein Overview: Arc42-PA

General Information:
Name(s) found: Arc42-PA / FBpp0083227 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene Arc42 is referred to in FlyBase by the symbol Dmel\Arc42 (CG4703, FBgn0038742). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:15703470..15705034. It has the cytological map location 92B4. Based on sequence similarity, it is predicted to have molecular function</span>: acyl-CoA dehydrogenase activity; RNA polymerase II transcription mediator activity. There is experimental evidence that it is involved in the biological process</span>: dendrite morphogenesis. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 405 amino acids

    Gene Ontology:
    Cellular Component: mediator complex [ISS]
    Biological Process: oxidation reduction [IEA]
    transcription initiation from RNA polymerase II promoter [ISS]
    dendrite morphogenesis [IMP]
    Molecular Function: acyl-CoA dehydrogenase activity [ISS]
    FAD binding [IEA]
    RNA polymerase II transcription mediator activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQSVLTRSLC IARRSLNARQ IASLSALSET HQMLQKSCRD FANNELSGNA AKFDREHLYP  60
   61 EKQIRQMGEL GVMAVAIPEE LGGTGLDYVA YAIAMEEISR GCASAGVIMS VNNSLYLGPL 120
  121 LSFGNDAQKK DYITPFTTGE RVGCFALSEP GNGSDAGAAS TIATDKGDHF VLNGTKAWIT 180
  181 NAFEAEAAIV FATTNKQLKH KGISAFIVPK ATKGFSLGKK EDKLGIRGSS TCQLIFEDCV 240
  241 VPKENMLGEP GFGFKIAMQT LDAGRIGIAG QALGIGQAAL ELAVDYAQKR QAFGKPIAKL 300
  301 QSIQQKIADM SLAMESARLL TWRAAWLKDQ KQPYTKEAAM AKLAASEAAT LCSHQCIQIL 360
  361 GGMGYVTDMA AERHYRDARI TEIYEGTSEI QRLVIAGSIL KEYAS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..405] PSI-BLAST 123.0 Butyryl-CoA dehydrogenase, C-domain; Butyryl-CoA dehydrogenase, NM domains


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.71

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle