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Protein Overview: Ino80-PA

General Information:
Name(s) found: Ino80-PA / FBpp0083185 [FlyBase]
Description(s) found:
Found 18 descriptions.
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  • The gene Ino80 is referred to in FlyBase by the symbol Dmel\Ino80 (CG31212, FBgn0086613). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:15194717..15228870. It has the cytological map location 92A2-92A3. Based on sequence similarity, it is predicted to have molecular function</span>: helicase activity. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1638 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    Ino80 complex [IDA]
    Biological Process: NONE FOUND
    Molecular Function: ATP binding [IEA]
    DNA binding [IEA]
    helicase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEAKPVPAPQ PRPRAMAEPL HIQRLEAALN MRPFMNMAKR SLRKPLSSDE ETDDEHVVKR  60
   61 EHDVQDSDDS STVGVVRMKQ SSKRKSRLLA SKEERQSVKA QLYNFNDLTS DREWLYDLLL 120
  121 SDTESDDPTI TEDEYVQQLL REHVREQRQR KNYYKKAANA QYAYYGSGLL SNHDIFAERQ 180
  181 LATAGVRKRR RRTKQEILMA RLAEAQAGPK PPKQRRRGRK KRDNMGSPES GEVPPSELGK 240
  241 YTFGDTLPNN EDDDEDGGEV DYKRELASLA LDYPEEEEIE EEVDVEGGTE GQVTKVRRKR 300
  301 KNPAALAARR RRIWQIMSKK ESGRLQRIKS NNHKEMLANC KRVAGMCAKV VRQRAINSQR 360
  361 IMKETVWRAK RLTREMLAYW KRYERVERDQ RRKQEREAEE QRKQDVELIE VKRQQRKLNF 420
  421 LITQTELYAH FMSKKLGQGS EEDQLRILSQ LDEETNARLA AQDDYDAGEM KLLAQENAEA 480
  481 AMQRDLDKTR AFDVFAKKKE KEEEEQAQES VEDIKPEPRP EMKDLPQPKM FKGTLKGYQI 540
  541 KGMTWLANIY DQGISGILAD EMGLGKTVQS IAFLCHIAEH YGVWGPFLVI SPASTLHNWQ 600
  601 QEMSRFVPDF KVVPYWGSPA ERKILRQFWD QKHLHTRDAS FHVVITSYQL VVSDYKYFNR 660
  661 IKWQYMVLDE AQAIKSAASQ RWKLLLGFSC RNRLLLSGTP IQNSMAELWA LLHFIMPTLF 720
  721 DSHDEFNEWF SKDIESHAEN KTGIDEKQIS RLHMILKPFM LRRIKKDVEN ELSDKIEIMV 780
  781 YCPLTIRQKL LYRALKQKIR IEDLLHLTSG STTTSSSSSA SNLMNLVMQF RKVCNHPELF 840
  841 ERRDARSPFF MRCAEYTIPR LIHEEGLIHR MLPSRKHLLY NRFNIFKSEY IQRSLFEDVN 900
  901 VNSCFGFTRL CDLSVGDMVE VTLNGLIDFL LHYRRVLEKY PLLAYRRFWW KKQPDSRYQL 960
  961 LEPMLENKLA LDYMPPNSVL KNFIFTAMTA NESSVYAFGD YFTYNMQETI EHRVIRSKIL1020
 1021 KKKTSLIEEM EDVSKQKLEI ESVEVQTKSN AKSDVKVTTL LLLPEFPHRP RKPRKYVCEP1080
 1081 LSMPRILYDL GQKVQAVHRY LYCDSRSAAW SQIRHNQCEN SQGRELVSSG LALCKPHGGW1140
 1141 SSIVVPDKET LITDAGKLFV LDNLLTRLKA NGHRVLIYSQ MTKMIDLLEE YMWHRKHRYM1200
 1201 RLDGSSKISA RRDMVADFQT RADIFVFLLS TRAGGLGINL TAADTVIFYD SDWNPTVDQQ1260
 1261 AMDRAHRLGQ TKQVTVYRLI CKGTIEERIL QRAREKSEIQ RMVISGGNFK PDTLKPKEVV1320
 1321 SLLLDDEEIE MKYRQEAKLQ SSSPIPAATQ SERKRRHPQK DVNMGGTTIA ATSATQNPDD1380
 1381 DVPSCSSAAK RIKLETEEDF IDVGITSSAS SVGTDSNHPT LSQETYVPGA TCVQQTEIDS1440
 1441 ENEALVVDGD SPTMLGQNES MNFLDDLSGI SPMRRRHHPR GTRRGRPRGS TRRGGGHGSI1500
 1501 PRVLTPTQAA TPAVPATASQ AAAAGTGAAA GTSSPLPQQE VSGGGDNAGV PLHEEEYRTS1560
 1561 PSGQSPGVSC KRGPGRPRSK TATPISRGTR GAPRARRPMG PLLVPLGRSP DDTPPSSSPA1620
 1621 TSRAPSPLSG SHGAVGPE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..332] PSI-BLAST 14.69897 Heavy meromyosin subfragment
    2 View Details [333..523] deduced N/A No confident structure predictions are available.
    3 View Details [524..1073] PSI-BLAST 91.221849 Sulfolobus solfataricus SWI2/SNF2 ATPase core in complex with dsDNA
    4 View Details [1074..1280] PSI-BLAST 46.39794 Sulfolobus solfataricus SWI2/SNF2 ATPase C-terminal domain
    5 View Details [1281..1638] PSI-BLAST 4.0 Fibrinogen


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
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