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Protein Overview: cdi-PA

General Information:
Name(s) found: cdi-PA / FBpp0083130 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene center divider is referred to in FlyBase by the symbol Dmel\cdi (CG6027, FBgn0004876). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:14870604..14920076. It has the cytological map location 91E4-91F1. Based on sequence similarity, it is predicted to have molecular function</span>: protein serine/threonine kinase activity. There is experimental evidence that it is involved in the biological process</span>: embryonic development via the syncytial blastoderm. 46 alleles are reported. The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; embryonic head; embryonic segment; macrochaeta; intersegmental nerve; nervous system; segment; head. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1213 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: embryonic development via the syncytial blastoderm [IMP]
    protein amino acid phosphorylation [IEA][ISS][NAS]
    Molecular Function: ATP binding [IEA]
    protein tyrosine kinase activity [IEA]
    protein kinase activity [NAS]
    protein serine/threonine kinase activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLNQHSGPG PPSEICGLSV DQVDSSAASP FIWPSTAGMC TTATTVTTST NGDATAEAPV  60
   61 KHQPLHNGGW IGNGLPPAPV TRTISSDRLV TGSSCRALRT AVSALYSVDD FVKEKIGSGF 120
  121 FSEVYKVTHR TTGQVMVLKM NQLRANRPNM LREVQLLNKL SHANILSFMG VCVQEGQLHA 180
  181 LTEYINGGSL EQLLANKEVV LSATQKIRLA LGIARGMSYV HDAGIFHRDL TSKNVLIRNL 240
  241 ANDQYEAVVG DFGLAAKIPV KSRKSRLETV GSPYWVSPEC LKGQWYDQTS DVFSFGIIQC 300
  301 EIIARIEADP DMMPRTASFG LDYLAFVELC PMDTPPVFLR LAFYCCLYDA KSRPTFHDAT 360
  361 KKLTLLLEKY EHESSAGASP LSSLELINCS PGGSDSENVT LTPRASVPTV ATICTAPAGT 420
  421 LTPRHLQEVD EDGFRFPSKK SASAALPGTP NGSAGSSGFD DHILKSRVRR ATQKLEAEIL 480
  481 LHRRSLSENI IHFPMHTSPS DKARCHQMQR QRSSTHSPTP PRQLSSVQLP ATSIPDPPPL 540
  541 PKPVPAVLTL RKVGDPQYKP TSEKDHNGSK PNPFEALAQL RGVKKILDAN PKTYAAGVGD 600
  601 LFSSCFEMLA PFFKELAAMQ SKAGAQGGGT STEETSTGNK ASAATPSEPK SLPVSPHMTR 660
  661 KYSAIELRLP QRISNAAPPA VTSAPPPSIA LPTDEDDCDD CNSEGEDPDG GGNCADAESS 720
  721 SDDSAVRPST VPTARKYRAN SLYAHPLFRG SNGTSMKSTS TGEFESPTLL KASASTITLT 780
  781 ASVGATNSCE DLTESARKSK EQASSGATAA VQALPTPMSG CSTRLVETPV SVSSCTDLEL 840
  841 DELKNTCDLN ELKNSCEQLP LKTNLTRRDS IESGFFSCFN EESDAAITNN SFGRQLNGIG 900
  901 SLGFGCGGGG NSSNCCYEKL KTQLMLDACV SADSEINDKL ASLCRCCYYA TSTSNAAVTA 960
  961 AAAAAQQQQQ SHLLNDTSST SSSVLLIDND PAVIGGNTSS STALDSMDDL DADIVASRRT1020
 1021 HQRRYTCHHA LLSGNGSESQ MAATASLINR LALDSEIHTL LQRSPFATNQ LLYCKNRTSS1080
 1081 IYTDSSDDIS SLAGSDSLLW DDRSFTALPS TRSAQIAKIV EYFERKRQDS SPPSVHHRNG1140
 1141 NGTVAAAVAA SALGSNYLSY ESRRYSDFKR HLNADGLCFD LDKKPAQQRM MVCEGAVKSK1200
 1201 LPIFDKKKQQ QGG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..98] PSI-BLAST 87.045757 Abl tyrosine kinase, SH3 domain; Abl tyrosine kinase; Abelsone tyrosine kinase (abl)
    2 View Details [99..327] PSI-BLAST 30.69897 No description for 1wakA was found.
    3 View Details [328..376] FFAS03 3.1 No description for 2ivsA was found.
    4 View Details [377..421] PSI-BLAST 75.154902 Catalytic and ubiqutin-associated domains of MARK2/PAR-1: Wild type
    5 View Details [422..537] deduced N/A No confident structure predictions are available.
    6 View Details [538..623] deduced N/A No confident structure predictions are available.
    7 View Details [624..719] deduced N/A No confident structure predictions are available.
    8 View Details [720..832] deduced N/A No confident structure predictions are available.
    9 View Details [833..936] PSI-BLAST 10.39794 Solution structure of the F-actin binding domain of Bcr-Abl/c-Abl
    10 View Details [937..989] deduced N/A No confident structure predictions are available.
    11 View Details [990..1096] deduced N/A No confident structure predictions are available.
    12 View Details [1097..1213] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein binding
    		•  1.85368024495439 bayes_pls_golite062009
  • binding
    		•  1.57485356549468 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.
    8 No functions predicted.
    9 No functions predicted.
    10 No functions predicted.
    11 No functions predicted.
    12 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.81

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle