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Protein Overview: gatA-PA

General Information:
Name(s) found: gatA-PA / FBpp0083132 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene glutamyl-tRNA amidotransferase subunit A is referred to in FlyBase by the symbol Dmel\gatA (CG6007, FBgn0260779). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:14851896..14854558. It has the cytological map location 91E4-91F2. Based on sequence similarity, it is predicted to have molecular function</span>: glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity. There is experimental evidence that it is involved in the biological process</span>: oogenesis; karyosome formation. 15 alleles are reported. The phenotypes of these alleles are annotated with: larval salivary gland; imaginal disc; larval brain. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 508 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [IDA]
    Biological Process: oogenesis [IMP]
    karyosome formation [IMP]
    translation [IEA]
    Molecular Function: glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRRHLQWSIK QLTASYSDGQ LSPRRVTEDA LQDALRWKTL NAFVRLTPEQ AGQQAQDAEQ  60
   61 RYKLRQPISD LDGVTIAIKD NFCTKDVHTT CASRMLQDFV PPYDATVCSR LKQAGAVILG 120
  121 KTNMDQFAMG AGTVDSLYGP TKNIWSEDLN KDHWRIAGGS SGGSASAVAA GLCYAAIGSD 180
  181 TGGSTRNPAS YCGVVGLKPT YGLVSRHGLI PLVNSMDVPG IFARSVSDCV AVLNTVAGPD 240
  241 KLDSTTIRQP FTRLHLPEVG QIDLSTVRIG IPKEYHCHGL SAEVLETWSK VADLLECSGA 300
  301 SVRQVSLPNT AASIFVYTIL NQCEVASNMA RYDGIEYGHR ATDERSTEQL YALSRAEGFN 360
  361 DVVKTRILTG NFLLLKKNYD HYFEKALRVR RLIAEDFARV FDSSAKEERV DILLTPTTLT 420
  421 EAPLYKDFAS LTNRDQCAVQ DFCTQPANMA GIPAVSIPIR LSQAGLPLSL QLMSNSLNEQ 480
  481 LLLTVARWIE AQVEFDSLEH SQQYKASL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..508] PSI-BLAST 136.0 No description for 2df4A was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
    		•  7.42914157198604 bayes_pls_golite062009
  • ligase activity
    		•  3.16753436373904 bayes_pls_golite062009
  • binding
    		•  1.29965583137169 bayes_pls_golite062009
  • catalytic activity
    		•  0.906509857495572 bayes_pls_golite062009
  • protein binding
    		•  0.583347864945253 bayes_pls_golite062009
  • hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
    		•  0.301483171038292 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.84

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle