Protein Overview: osa-PD, osa-PB

General Information:
Name(s) found:	osa-PD / FBpp0290702 [FlyBase] osa-PB / FBpp0088543 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|33301341\|sp\|Q8IN94.1\|OSA_DROME RecName: Full=Trithorax group protein osa; AltName: Full=Protein eyelid [NCBI NR] gi\|24647757\|ref\|NP_524392.2\| osa, isoform B [Drosophila melanogaster] [NCBI NR] gi\|23171573\|gb\|AAN13750.1\| osa, isoform B [Drosophila melanogaster] [NCBI NR] Trithorax group protein osa OS=Drosophila melanogaster GN=osa PE=1 SV=1 [Swiss-Prot] The gene osa is referred to in FlyBase by the symbol Dmel\osa (CG7467, FBgn0003013). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:13513540..13544059. It has the cytological map location 90C1-90C2. There is experimental evidence that it has the molecular function</span>: SUMO binding; DNA binding. There is experimental evidence that it is involved in the biological process</span>: photoreceptor cell differentiation; segment specification; imaginal disc-derived wing margin morphogenesis; wing disc dorsal/ventral pattern formation; regulation of transcription; positive regulation of transcription, DNA-dependent; imaginal disc-derived wing morphogenesis; Wnt receptor signaling pathway. 61 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: adult segment; peripheral nervous system; adult mesothoracic segment; nervous system; organ system; dorsal thoracic disc; external compound sense organ; Malpighian tubule; larval thorax; compound cell cluster organ; imaginal precursor. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase] >CG7467-PB translation from_gene[CG7467 osa FBgn0003013] seq_release:3 mol_weight=284067 cds_boundaries:(3R:13,515,558..13,542,503[-]) aa_length:2716 transcript_info:[CG7467-RB seq_release:3] gene_info:[gene symbol:osa FBgn0003013 gene_boundaries:(3R:1 [hmr_yeast5_DM3-1_pombe.fasta] (Q8IN94) Trithorax group protein OSA (Eyelid protein) [DrosMelano7227.FASTAC.txt] CG7467-PB, isoform B [Drosophila melanogaster]gi\|24647757\|ref\|NP_524392.2\| CG7467-PB [Drosophila melanogaster]gi\|33301341\|sp\|Q8IN94\|OSA_DROME Trithorax group protein OSA (Eyelid protein) [nrdb_11152004_Chlamydomonas] type=protein; loc=3R:complement(13515540..13519177,13519246..13519327,13519437..13519635,13519858..13520017,13520556..13521035,13521645..13521872,13522092..13522308,13523387..13523638,13523703..13523884,13523952..13524686,13524817..13525209,13525269..1352 [fly-100309-contam.fasta] osa CG7467-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] CG7467-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] Trithorax group protein osa (Protein eyelid) [nr-271106-contam.fasta] type=protein; loc=3R:complement(13515540..13519177,13519246..13519327,13519437..13519635,13519858..13520017,13520556..13521035,13521645..13521872,13522092..13522308,13523387..13523638,13523703..13523884,13523952..13524686,13524817..13525209,13525269..13525425,13533493..13533711,13533776..13534069,13541574..13542488); ID=FBpp0088543; name=osa-PB; parent=FBgn0003013,FBtr0089581; dbxref=FlyBase:FBpp0088543,FlyBase_Annotation_IDs:CG7467-PB,GB_protein:AAN13750.1,REFSEQ:NP_524392,GB_protein:AAN13750; MD5=761b482b4ab3ae722d8f020f8ba8c33e; length=2716; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=3R:complement(13515540..13519177,13519246..13519327,13519437..13519635,13519858..13520017,13520556..13521035,13521645..13521872,13522092..13522308,13523387..13523638,13523703..13523884,13523952..13524686,13524817..13525209,13525269..13525425,13533493..13533711,13533776..13534069,13541574..13542488); ID=FBpp0088543; name=osa-PB; parent=FBgn0003013,FBtr0089581; dbxref=FlyBase:FBpp0088543,FlyBase_Annotation_IDs:CG7467-PB,GB_protein:AAN13750.1,REFSEQ:NP_524392,GB_protein:AAN13750; MD5=761b482b4ab3ae722d8f020f8ba8c33e; length=2716; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] type=protein; loc=3R:complement(13515540..13519177,13519246..13519327,13519437..13519635,13519858..13520017,13520556..13521035,13521645..13521872,13522092..13522308,13523387..13523638,13523703..13523884,13523952..13524686,13524817..13525209,13525269..13525425,13533493..13533711,13533776..13534069,13541574..13542488); ID=FBpp0290702; name=osa-PD; parent=FBgn0003013,FBtr0301487; dbxref=FlyBase:FBpp0290702,FlyBase_Annotation_IDs:CG7467-PD; MD5=761b482b4ab3ae722d8f020f8ba8c33e; length=2716; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Osa, isoform D OS=Drosophila melanogaster GN=osa PE=4 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=3R:complement(13515540..13519177,13519246..13519327,13519437..13519635,13519858..13520017,13520556..13521035,13521645..13521872,13522092..13522308,13523387..13523638,13523703..13523884,13523952..13524686,13524817..13525209,13525269..13525425,13533493..13533711,13533776..13534069,13541574..13542488); ID=FBpp0290702; name=osa-PD; parent=FBgn0261885,FBtr0301487; dbxref=REFSEQ:NP_001163639,GB_protein:ACZ94935,FlyBase:FBpp0290702,FlyBase_Annotation_IDs:CG7467-PD,FlyMine:FBpp0290702,modMine:FBpp0290702; MD5=761b482b4ab3ae722d8f020f8ba8c33e; length=2716; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3R:complement(13515540..13519177,13519246..13519327,13519437..13519635,13519858..13520017,13520556..13521035,13521645..13521872,13522092..13522308,13523387..13523638,13523703..13523884,13523952..13524686,13524817..13525209,13525269..13525425,13533493..13533711,13533776..13534069,13541574..13542488); ID=FBpp0088543; name=osa-PB; parent=FBgn0261885,FBtr0089581; dbxref=FlyBase:FBpp0088543,FlyBase_Annotation_IDs:CG7467-PB,GB_protein:AAN13750.1,REFSEQ:NP_524392,GB_protein:AAN13750; MD5=761b482b4ab3ae722d8f020f8ba8c33e; length=2716; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3R:complement(join(17715852..17716766,17708054..17708347,17707771..17707989,17699547..17699703,17699095..17699487,17698230..17698964,17697981..17698162,17697665..17697916,17696370..17696586,17695923..17696150,17694834..17695313,17694136..17694295,17693715..17693913,17693524..17693605,17689818..17693455)); ID=FBpp0290702; name=osa-PD; parent=FBgn0261885,FBtr0301487; dbxref=REFSEQ:NP_001163639,GB_protein:ACZ94935,FlyBase:FBpp0290702,FlyBase_Annotation_IDs:CG7467-PD,FlyMine:FBpp0290702,modMine:FBpp0290702; MD5=761b482b4ab3ae722d8f020f8ba8c33e; length=2716; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3R:complement(join(17715852..17716766,17708054..17708347,17707771..17707989,17699547..17699703,17699095..17699487,17698230..17698964,17697981..17698162,17697665..17697916,17696370..17696586,17695923..17696150,17694834..17695313,17694136..17694295,17693715..17693913,17693524..17693605,17689818..17693455)); ID=FBpp0088543; name=osa-PB; parent=FBgn0261885,FBtr0089581; dbxref=FlyBase:FBpp0088543,FlyBase_Annotation_IDs:CG7467-PB,GB_protein:AAN13750.1,REFSEQ:NP_524392,GB_protein:AAN13750; MD5=761b482b4ab3ae722d8f020f8ba8c33e; length=2716; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3R:complement(join(17715852..17716766,17708054..17708347,17707771..17707989,17699547..17699703,17699095..17699487,17698230..17698964,17697981..17698162,17697665..17697916,17696370..17696586,17695923..17696150,17694834..17695313,17694136..17694295,17693715..17693913,17693524..17693605,17689818..17693455)); ID=FBpp0290702; name=osa-PD; parent=FBgn0261885,FBtr0301487; dbxref=REFSEQ:NP_001163639,GB_protein:ACZ94935,FlyBase:FBpp0290702,FlyBase_Annotation_IDs:CG7467-PD,FlyMine:FBpp0290702,modMine:FBpp0290702; MD5=761b482b4ab3ae722d8f020f8ba8c33e; length=2716; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] type=protein; loc=3R:complement(join(17715852..17716766,17708054..17708347,17707771..17707989,17699547..17699703,17699095..17699487,17698230..17698964,17697981..17698162,17697665..17697916,17696370..17696586,17695923..17696150,17694834..17695313,17694136..17694295,17693715..17693913,17693524..17693605,17689818..17693455)); ID=FBpp0088543; name=osa-PB; parent=FBgn0261885,FBtr0089581; dbxref=FlyBase:FBpp0088543,FlyBase_Annotation_IDs:CG7467-PB,GB_protein:AAN13750.1,REFSEQ:NP_524392,GB_protein:AAN13750; MD5=761b482b4ab3ae722d8f020f8ba8c33e; length=2716; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Isoform of Q8IN94, Osa, isoform D OS=Drosophila melanogaster GN=osa PE=1 SV=1 [DROME.fasta.20160308] FBpp0290702 type=protein; loc=3R:complement(join(17715852..17716766,17708054..17708347,17707771..17707989,17699547..17699703,17699095..17699487,17698230..17698964,17697981..17698162,17697665..17697916,17696370..17696586,17695923..17696150,17694834..17695313,17694136..17694295,17693715..17693913,17693524..17693605,17689818..17693455)); ID=FBpp0290702; name=osa-PD; parent=FBgn0261885,FBtr0301487; dbxref=REFSEQ:NP_001163639,GB_protein:ACZ94935,FlyBase:FBpp0290702,FlyBase_Annotation_IDs:CG7467-PD,FlyMine:FBpp0290702,modMine:FBpp0290702; MD5=761b482b4ab3ae722d8f020f8ba8c33e; length=2716; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] FBpp0088543 type=protein; loc=3R:complement(join(17715852..17716766,17708054..17708347,17707771..17707989,17699547..17699703,17699095..17699487,17698230..17698964,17697981..17698162,17697665..17697916,17696370..17696586,17695923..17696150,17694834..17695313,17694136..17694295,17693715..17693913,17693524..17693605,17689818..17693455)); ID=FBpp0088543; name=osa-PB; parent=FBgn0261885,FBtr0089581; dbxref=FlyBase:FBpp0088543,FlyBase_Annotation_IDs:CG7467-PB,GB_protein:AAN13750.1,REFSEQ:NP_524392,GB_protein:AAN13750; MD5=761b482b4ab3ae722d8f020f8ba8c33e; length=2716; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3R:complement(join(17715852..17716766,17708054..17708347,17707771..17707989,17699547..17699703,17699095..17699487,17698230..17698964,17697981..17698162,17697665..17697916,17696370..17696586,17695923..17696150,17694834..17695313,17694136..17694295,17693715..17693913,17693524..17693605,17689818..17693455)); ID=FBpp0290702; name=osa-PD; parent=FBgn0261885,FBtr0301487; dbxref=REFSEQ:NP_001163639,GB_protein:ACZ94935,FlyBase:FBpp0290702,FlyBase_Annotation_IDs:CG7467-PD,UniProt/Swiss-Prot:Q8IN94,FlyMine:FBpp0290702,modMine:FBpp0290702; MD5=761b482b4ab3ae722d8f020f8ba8c33e; length=2716; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta] type=protein; loc=3R:complement(join(17715852..17716766,17708054..17708347,17707771..17707989,17699547..17699703,17699095..17699487,17698230..17698964,17697981..17698162,17697665..17697916,17696370..17696586,17695923..17696150,17694834..17695313,17694136..17694295,17693715..17693913,17693524..17693605,17689818..17693455)); ID=FBpp0088543; name=osa-PB; parent=FBgn0261885,FBtr0089581; dbxref=FlyBase:FBpp0088543,FlyBase_Annotation_IDs:CG7467-PB,GB_protein:AAN13750.1,REFSEQ:NP_524392,GB_protein:AAN13750,UniProt/Swiss-Prot:Q8IN94; MD5=761b482b4ab3ae722d8f020f8ba8c33e; length=2716; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	2716 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA][NAS] brahma complex [IDA][TAS]
Biological Process:	photoreceptor cell differentiation [IMP] positive regulation of transcription, DNA-dependent [IDA] imaginal disc-derived wing morphogenesis [IMP] Wnt receptor signaling pathway [IMP] imaginal disc-derived wing margin morphogenesis [IMP] wing disc dorsal/ventral pattern formation [IGI] regulation of transcription [IDA][IMP] segment specification [IMP]
Molecular Function:	DNA binding [IDA][ISS][NAS] SUMO binding [IPI] transcription coactivator activity [IC]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNEKIKSPQT QQQQQGGAPA PAATPPSAGA APGAATPPTS GPPTPNNNSN NGSDPSIQQQ  60
   61 QQNVAPHPYG APPPPGSGPG GPPGPDPAAV MHYHHLHQQQ QQHPPPPHMQ QQQHHGGPAP 120
  121 PPPGGAPEHA PGVKEEYTHL PPPHPHPAYG RYHADPNMDP YRYGQPLPGG KPPQQQQPHP 180
  181 QQQPPQQPGP GGSPNRPPQQ RYIPGQPPQG PTPTLNSLLQ SSNPPPPPQH RYANTYDPQQ 240
  241 AAASAAAAAA AQQQQAGGPP PPGHGPPPPQ HQPSPYGGQQ GGWAPPPRPY SPQLGPSQQY 300
  301 RTPPPTNTSR GQSPYPPAHG QNSGSYPSSP QQQQQQQQQQ QQQAGQQPGG PVPGGPPPGT 360
  361 GQQPPQQNTP PTSQYSPYPQ RYPTPPGLPA GGSNHRTAYS THQYPEPNRP WPGGSSPSPG 420
  421 SGHPLPPASP HHVPPLQQQP PPPPHVSAGG PPPSSSPGHA PSPSPQPSQA SPSPHQELIG 480
  481 QNSNDSSSGG AHSGMGSGPP GTPNPQQVMR PTPSPTGSSG SRSMSPAVAQ NHPISRPASN 540
  541 QSSSGGPMQQ PPVGAGGPPP MPPHPGMPGG PPQQQQSQQQ QASNSASSAS NSPQQTPPPA 600
  601 PPPNQGMNNM ATPPPPPQGA AGGGYPMPPH MHGGYKMGGP GQSPGAQGYP PQQPQQYPPG 660
  661 NYPPRPQYPP GAYATGPPPP PTSQAGAGGA NSMPSGAQAG GYPGRGMPNH TGQYPPYQWV 720
  721 PPSPQQTVPG GAPGGAMVGN HVQGKGTPPP PVVGGPPPPQ GSGSPRPLNY LKQHLQHKGG 780
  781 YGGSPTPPQG PQGYGNGPTG MHPGMPMGPP HHMGPPHGPT NMGPPTSTPP QSQMLQGGQP 840
  841 QGQGASGGPE SGGPEHISQD NGISSSGPTG AAGMHAVTSV VTTGPDGTSM DEVSQQSTLS 900
  901 NASAASGEDP QCTTPKSRKN DPYSQSHLAP PSTSPHPVVM HPGGGPGEEY DMSSPPNWPR 960
  961 PAGSPQVFNH VPVPQEPFRS TITTTKKSDS LCKLYEMDDN PDRRGWLDKL RAFMEERRTP1020
 1021 ITACPTISKQ PLDLYRLYIY VKERGGFVEV TKSKTWKDIA GLLGIGASSS AAYTLRKHYT1080
 1081 KNLLTFECHF DRGDIDPLPI IQQVEAGSKK KTAKAASVPS PGGGHLDAGT TNSTGSSNSQ1140
 1141 DSFPAPPGSA PNAAIDGYPG YPGGSPYPVA SGPQPDYATA GQMQRPPSQN NPQTPHPGAA1200
 1201 AAVAAGDNIS VSNPFEDPIA AGGGPGSGTG PGPGQGPGPG AASGGAGAVG AVGGGPQPHP1260
 1261 PPPHSPHTAA QQAAGQHQQQ HPQHQHPGLP GPPPPQQQQG QQGQQPPPSV GGGPPPAPQQ1320
 1321 HGPGQVPPSP QQHVRPAAGA PYPPGGSGYP TPVSRTPGSP YPSQPGAYGQ YGSSDQYNAT1380
 1381 GPPGQPFGQG PGQYPPQNRN MYPPYGPEGE APPTGANQYG PYGSRPYSQP PPGGPQPPTQ1440
 1441 TVAGGPPAGG APGAPPSSAY PTGRPSQQDY YQPPPDQSPQ PRRHPDFIKD SQPYPGYNAR1500
 1501 PQIYGAWQSG TQQYRPQYPS SPAPQNWGGA PPRGAAPPPG APHGPPIQQP AGVAQWDQHR1560
 1561 YPPQQGPPPP PQQQQQPQQQ QQQPPYQQVA GPPGQQPPQA PPQWAQMNPG QTAQSGIAPP1620
 1621 GSPLRPPSGP GQQNRMPGMP AQQQQSQQQG GVPQPPPQQA SHGGVPSPGL PQVGPGGMVK1680
 1681 PPYAMPPPPS QGVGQQVGQG PPGGMMSQKP PPMPGQAMQQ QPLQQQPPSH QHPHPHQHPQ1740
 1741 HQHPHQMPPN QTAPGGYGPP GMPGGGAQLV KKELIFPHDS VESTTPVLYR RKRLMKADVC1800
 1801 PVDPWRIFMA MRSGLLTECT WALDVLNVLL FDDSTVQFFG ISNLPGLLTL LLEHFQKNLA1860
 1861 EMFDERENEE QSALLAEDAD DDADSGTVMC EKLRTSGRQP RCVRSISSYN RRRHYENMDR1920
 1921 SGKDGAGNGS DSEDADEGID LGQVRVQPNP EERSLLLSFT PNYTMVTRKG VPVRIQPAEN1980
 1981 DIFVDERQKA WDIDTNRLYE QLEPVGSDAW TYGFTEPDPL DGIIDVFKSE IVNIPFARYI2040
 2041 RSDKKGRKRT ELASSSRKPE IKTEENSTEE QTFNKKRRLV SGGSSSSGAH AEGKKSKLTS2100
 2101 EEFAQPNAEV KKEPGTADSD CRPVDMDIEA PQQRLTNGVA PCSSTPAIFD PRTTAKDEAR2160
 2161 VLQRRRDSSF EDECYTRDEA SLHLVSESQD SLARRCIALS NIFRNLTFVP GNETVLAKST2220
 2221 RFLAVLGRLL LLNHEHLRRT PKTRNYDREE DTDFSDSCSS LQGEREWWWD YLITIRENML2280
 2281 VAMANIAGHL ELSRYDELIA RPLIDGLLHW AVCPSAHGQD PFPSCGPNSV LSPQRLALEA2340
 2341 LCKLCVTDAN VDLVIATPPF SRLEKLCAVL TRHLCRNEDQ VLREFSVNLL HYLAAADSAM2400
 2401 ARTVALQSPC ISYLVAFIEQ AEQTALGVAN QHGINYLREN PDSMGTSLDM LRRAAGTLLH2460
 2461 LAKHPDNRSL FMQQEQRLLG LVMSHILDQQ VALIISRVLY QVSRGTGPIH SVEFRLLQQR2520
 2521 QQQQLRPGPA GKQAASAGGS ATVKAETAST ETSSTEAKPA PAATTAVVND ENSNSSQQLP2580
 2581 PAATFNDVSN SSTNSNSCGT ASSNQTNNST TNSSHSSSAI SSQSAITVAA PSAAATGAGS2640
 2641 ATAAAIASDQ QQVSKVAAAA AAAAALSNAS AAAAAAAAAA AASVGPPTSS SVSAGAAVAQ2700
 2701 PAAPPPTNAG TTTAVA

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: osa-PD, osa-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: