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Protein Overview: GckIII-PA

General Information:
Name(s) found: GckIII-PA / FBpp0082840 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene Germinal centre kinase III is referred to in FlyBase by the symbol Dmel\GckIII (CG5169, FBgn0086736). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:12911256..12913620. It has the cytological map location 89E12. It is reported to have molecular function</span>: receptor signaling protein serine/threonine kinase activity. There is experimental evidence that it is involved in the biological process</span>: actin filament organization. 9 alleles are reported. The phenotypes of these alleles are annotated with: dorsal mesothoracic disc; wing. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 642 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: actin filament organization [IMP]
    protein amino acid phosphorylation [IEA][NAS]
    Molecular Function: ATP binding [IEA]
    receptor signaling protein serine/threonine kinase activity [NAS]
    protein serine/threonine kinase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSWTEKVDPE LIFTKQERIG KGSFGEVFKG IDNRTQQVVA IKIIDLEEAE DEIDDIQQEI  60
   61 MVLSQCDSPY VTKYYGSFLK GTKLWIIMEY LGGGSALDLM KAGSFEEMHI GIILREVLKG 120
  121 LDYLHSERKL HRDIKAANVL LSEQGDVKLA DFGVAGQLTN TTSKRNTFVG TPFWMAPEVI 180
  181 KQSQYDAKAD IWSLGITAIE LAKGEPPNSE LHPMRVLFLI PKNNPPQLTG SYTKSFKDFV 240
  241 EACLNKDPEN RPTAKELLKY PFIKKAKKNA YLIDLIDRFK KWKVSKGDES ETESENSDSD 300
  301 SDAKQGGSSQ DEPWIMTVKG LHINSAPRAG VNSFQLQEHE LTMQKLMQTT HSPAGGGGVQ 360
  361 ASPAANALSS SVSAVAASAS SVSVITANEG VSSASALPPQ NSHVHNHNHN NINNNNIRNL 420
  421 SNKHATTTML NAAPPPSSVT SSSSASELQQ KRSSSKPELR QSRSAAPLDQ VEDRRASLGL 480
  481 PLQSSVPTPS TAEQQQQRRS SQRESFHANN AALVASCSSS SNNHSHEEHV ATNHASHVKH 540
  541 SGAGQRLVQT NSACLNNFLF PVLSDIQRKY SGGGSAGSGG SGGRNIGVGS DIGDLKSVFE 600
  601 LAERSSPGVS DLFMKELIHM LVPGYSETRI NTIMDRAIRN RK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..350] PSI-BLAST 68.30103 pak1
    2 View Details [351..414] deduced N/A No confident structure predictions are available.
    3 View Details [415..642] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle