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Protein Overview: Sulf1-PA, FBpp03...

General Information:
Name(s) found: FBpp0306755 [FlyBase]
FBpp0306754 [FlyBase]
Sulf1-PA / FBpp0082725 [FlyBase]
Description(s) found:
Found 33 descriptions.
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  • type=protein; loc=3R:complement(12136903..12137014,12137083..12137185,12137249..12137446,12137523..12137833,12137895..12138757,12138828..12139491,12139546..12139872,12140087..12140853); ID=FBpp0306755; name=Sulf1-PC; parent=FBgn0040271,FBtr0334700; dbxref=FlyBase:FBpp0306755,FlyBase_Annotation_IDs:CG6725-PC,REFSEQ:NP_001262627,GB_protein:AGB96007; MD5=73a295802df890c254d5ea9754e481d5; length=1114; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=3R:complement(12136903..12137014,12137083..12137185,12137249..12137446,12137523..12137833,12137895..12138757,12138828..12139491,12139546..12139872,12140087..12140853); ID=FBpp0306754; name=Sulf1-PB; parent=FBgn0040271,FBtr0334699; dbxref=FlyBase:FBpp0306754,FlyBase_Annotation_IDs:CG6725-PB,REFSEQ:NP_001262626,GB_protein:AGB96006; MD5=73a295802df890c254d5ea9754e481d5; length=1114; release=r5.56; species=Dmel; [FlyBase]
  • The gene Sulfated is referred to in FlyBase by the symbol Dmel\Sulf1 (CG6725, FBgn0040271). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:12136256..12140853. It has the cytological map location 89B12. Based on sequence similarity, it is predicted to have molecular function</span>: N-acetylglucosamine-6-sulfatase activity; alkyl sulfatase activity. There is experimental evidence that it is involved in the biological process</span>: pattern specification process. 5 alleles are reported. The phenotype of these alleles is annotated with: imaginal tracheoblast. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1114 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [ISS]
    Golgi stack [ISS]
    cell surface [ISS]
    Biological Process: metabolic process [ISS]
    pattern specification process [IMP]
    Molecular Function: alkyl sulfatase activity [ISS]
    N-acetylglucosamine-6-sulfatase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMRHSSLRLI IGGLILLLFV LNVFSKEQGS HSHKRSHSAK RFSRDSNSAR ERRPNIILIL  60
   61 TDDQDVELGS LNFMPRTLRL LRDGGAEFRH AYTTTPMCCP ARSSLLTGMY VHNHMVFTNN 120
  121 DNCSSPQWQA THETRSYATY LSNAGYRTGY FGKYLNKYNG SYIPPGWREW GGLIMNSKYY 180
  181 NYSINLNGQK IKHGFDYAKD YYPDLIANDS IAFLRSSKQQ NQRKPVLLTM SFPAPHGPED 240
  241 SAPQYSHLFF NVTTHHTPSY DHAPNPDKQW ILRVTEPMQP VHKRFTNLLM TKRLQTLQSV 300
  301 DVAVERVYNE LKELGELDNT YIVYTSDHGY HLGQFGLIKG KSFPFEFDVR VPFLIRGPGI 360
  361 QASKVVNEIV LNVDLAPTFL DMGGVPTPQH MDGRSILPLL LSRNRAVRDN WPDSFLIESS 420
  421 GRRETAEQIA ESRARLQIER RNMKLANSSL LEDFLEGAGE STTIVSSSST AATLMSSTAQ 480
  481 QPEDGEEEVE TDNEEDDVDG DGAMDSSAAA LEEDDLDDAA FEEGDEELDQ EFQQNNDLPL 540
  541 APYITKMMRL NSECSDPALL KNCLPGQKWK CVNEEGRWRK HKCKFHLQLE HQLAAMPRKQ 600
  601 YQRNCACFTP DGVVYTKIRA PSAGLHRVNK RTHNGPGRRR NKREVFHTEL PDEMEELLDL 660
  661 HQVVDQLVDH THRSKRDLPA SSNETIAQVI QQIQSTLEIL ELKFNEHELH ASNSSGNSYE 720
  721 RGEKYTKSGG HRCFVDATTA KVNCSNVIYD DEKTWRTSRT QIDMLIKLLK DKIGKLKEMK 780
  781 KQLRESNKQA LAAGRRNDNR RRNDQSVLDS GAGPEFNMSY FTEISSTPRS NVVGQTEVFQ 840
  841 GYGSASAFDS LEQTQSHRFT PRAECYCEPD VGENHADSKE MAREARRKLK EERQRKKERK 900
  901 RIKKARLEKE CLSEKMNCFS HDNQHWRTAP LWNDSPFCFC MNANNNTYSC LRTINGTHNF 960
  961 LYCEFTTGLI TFYNLTIDRF ETINRAAGLT PGERSHMHDA LDQLKSCRGR SCSIRRHQNH1020
 1021 LEGGSSAPLL PINQVHRNNK RKHSPLAGAV GNYAFVGPRL DMEALPPIKR RKLSKYNRLT1080
 1081 GSQQSHMKRR PWKQTPLQQS PRFLRTHSVT PAQA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..508] PSI-BLAST 76.0 Structure of Human Placental Estrone/DHEA Sulfatase
    2 View Details [509..737] deduced N/A No confident structure predictions are available.
    3 View Details [738..910] MSA 2.027974 View MSA. No confident structure predictions are available.
    4 View Details [911..1033] MSA 3.029981 View MSA. No confident structure predictions are available.
    5 View Details [1034..1114] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • sulfuric ester hydrolase activity
    		•  3.86330883060982 bayes_pls_golite062009
  • catalytic activity
    		•  2.31328968099128 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  1.7864683378766 bayes_pls_golite062009
  • arylsulfatase activity
    		•  1.46195208030663 bayes_pls_golite062009
  • hydrolase activity
    		•  0.815218974563904 bayes_pls_golite062009
  • binding
    		•  0.699784512591091 bayes_pls_golite062009
  • protein binding
    		•  0.208332656410563 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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