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View Structure Prediction Details

Protein: Sulf1-PA, FBpp03...
Organism: Drosophila melanogaster
Length: 1114 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Sulf1-PA, FBpp03....

Description E-value Query
Range
Subject
Range
gi|21429186 - gi|21429186|gb|AAM50312.1| SD04414p [Drosophila melanogaster]
980.0 [0..109] [1114..1]

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Predicted Domain #1
Region A:
Residues: [1-508]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMRHSSLRLI IGGLILLLFV LNVFSKEQGS HSHKRSHSAK RFSRDSNSAR ERRPNIILIL  60
   61 TDDQDVELGS LNFMPRTLRL LRDGGAEFRH AYTTTPMCCP ARSSLLTGMY VHNHMVFTNN 120
  121 DNCSSPQWQA THETRSYATY LSNAGYRTGY FGKYLNKYNG SYIPPGWREW GGLIMNSKYY 180
  181 NYSINLNGQK IKHGFDYAKD YYPDLIANDS IAFLRSSKQQ NQRKPVLLTM SFPAPHGPED 240
  241 SAPQYSHLFF NVTTHHTPSY DHAPNPDKQW ILRVTEPMQP VHKRFTNLLM TKRLQTLQSV 300
  301 DVAVERVYNE LKELGELDNT YIVYTSDHGY HLGQFGLIKG KSFPFEFDVR VPFLIRGPGI 360
  361 QASKVVNEIV LNVDLAPTFL DMGGVPTPQH MDGRSILPLL LSRNRAVRDN WPDSFLIESS 420
  421 GRRETAEQIA ESRARLQIER RNMKLANSSL LEDFLEGAGE STTIVSSSST AATLMSSTAQ 480
  481 QPEDGEEEVE TDNEEDDVDG DGAMDSSA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 76.0
Match: 1p49A
Description: Structure of Human Placental Estrone/DHEA Sulfatase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
sulfuric ester hydrolase activity 3.86330883060982 bayes_pls_golite062009
catalytic activity 2.31328968099128 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 1.7864683378766 bayes_pls_golite062009
arylsulfatase activity 1.46195208030663 bayes_pls_golite062009
hydrolase activity 0.815218974563904 bayes_pls_golite062009
binding 0.699784512591091 bayes_pls_golite062009
protein binding 0.208332656410563 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [509-737]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AALEEDDLDD AAFEEGDEEL DQEFQQNNDL PLAPYITKMM RLNSECSDPA LLKNCLPGQK  60
   61 WKCVNEEGRW RKHKCKFHLQ LEHQLAAMPR KQYQRNCACF TPDGVVYTKI RAPSAGLHRV 120
  121 NKRTHNGPGR RRNKREVFHT ELPDEMEELL DLHQVVDQLV DHTHRSKRDL PASSNETIAQ 180
  181 VIQQIQSTLE ILELKFNEHE LHASNSSGNS YERGEKYTKS GGHRCFVDA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [738-910]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTAKVNCSNV IYDDEKTWRT SRTQIDMLIK LLKDKIGKLK EMKKQLRESN KQALAAGRRN  60
   61 DNRRRNDQSV LDSGAGPEFN MSYFTEISST PRSNVVGQTE VFQGYGSASA FDSLEQTQSH 120
  121 RFTPRAECYC EPDVGENHAD SKEMAREARR KLKEERQRKK ERKRIKKARL EKE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [911-1033]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CLSEKMNCFS HDNQHWRTAP LWNDSPFCFC MNANNNTYSC LRTINGTHNF LYCEFTTGLI  60
   61 TFYNLTIDRF ETINRAAGLT PGERSHMHDA LDQLKSCRGR SCSIRRHQNH LEGGSSAPLL 120
  121 PIN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [1034-1114]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QVHRNNKRKH SPLAGAVGNY AFVGPRLDME ALPPIKRRKL SKYNRLTGSQ QSHMKRRPWK  60
   61 QTPLQQSPRF LRTHSVTPAQ A

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle