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Protein Overview: gish-PE

General Information:
Name(s) found: gish-PE / FBpp0082719 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene gilgamesh is referred to in FlyBase by the symbol Dmel\gish (CG6963, FBgn0250823). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:12098176..12128094. It has the cytological map location 89B9-89B12. Based on sequence similarity, it is predicted to have molecular function</span>: protein serine/threonine kinase activity. There is experimental evidence that it is involved in the biological process</span>: glial cell migration; protein amino acid phosphorylation; Wnt receptor signaling pathway; spermatogenesis. 48 alleles are reported. The phenotypes of these alleles are annotated with: spermatogonium; eye; photoreceptor cell; ommatidium. It has 9 annotated transcripts and 9 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 463 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [IDA]
    Biological Process: spermatogenesis [IMP]
    Wnt receptor signaling pathway [IMP]
    protein amino acid phosphorylation [IDA][NAS]
    glial cell migration [IMP]
    Molecular Function: ATP binding [IEA]
    protein serine/threonine kinase activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQRRERQASG GGPQTTTAGP SAGNVANATT ALAGGKSSSN NMYSTRQSVS TTTGVLMVGP  60
   61 NFRVGKKIGC GNFGELRLGK NLYNNEHVAI KMEPMKSKAP QLHLEYRFYK LLGSHAEGVP 120
  121 EVYYFGPCGK YNALVMELLG PSLEDLFDIC GRRFTLKSVL LIAIQLLHRI EYVHSRHLIY 180
  181 RDVKPENFLI GRTSTKREKI IHIIDFGLAK EYIDLDTNRH IPYREHKSLT GTARYMSINT 240
  241 HMGREQSRRD DLEALGHMFM YFLRGSLPWQ GLKADTLKER YQKIGDTKRA TPIEVLCDGH 300
  301 PEEFATYLRY VRRLDFFETP DYDFLRRLFQ DLFDRKGYTD EGEFDWTGKT MSTPVGSLQT 360
  361 GHEVIISPNK DRHNVTAKTN AKGGVAAWPD VPKPGATLGN LTPADRHGSV QVVSSTNGEL 420
  421 NPDDPTAGHS NTPITQQPEV EVVDETKCCC FFKRKKKKST RQK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..406] PSI-BLAST 60.154902 No description for 2chlA was found.
    2 View Details [407..463] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle