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Protein Overview: FBpp0306751, ear-PA

General Information:
Name(s) found: FBpp0306751 [FlyBase]
ear-PA / FBpp0082538 [FlyBase]
Description(s) found:
Found 27 descriptions.
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  • type=protein; loc=3R:join(11147140..11147326,11147398..11150006); ID=FBpp0306751; name=ear-PC; parent=FBgn0026441,FBtr0334695; dbxref=FlyBase:FBpp0306751,FlyBase_Annotation_IDs:CG4913-PC,REFSEQ:NP_001262596,GB_protein:AGB95977; MD5=69c2eab1ceb396cbc31d476f694c8ce0; length=931; release=r5.56; species=Dmel; [FlyBase]
  • The gene ENL/AF9-related is referred to in FlyBase by the symbol Dmel\ear (CG4913, FBgn0026441). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:11146484..11150197. It has the cytological map location 88F1. Based on sequence similarity, it is predicted to have molecular function</span>: general RNA polymerase II transcription factor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: transcription initiation from RNA polymerase II promoter. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 931 amino acids

    Gene Ontology:
    Cellular Component: transcription factor TFIID complex [ISS]
    transcription factor TFIIF complex [ISS]
    Biological Process: regulation of transcription, DNA-dependent [IEA]
    transcription initiation from RNA polymerase II promoter [ISS]
    Molecular Function: general RNA polymerase II transcription factor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVKVQFEIG HTSKLRSKKT PHPQAFTHDW EIYVQGVNKA DISAFVEKVV FVLHESFPKP  60
   61 KRVVKEPPYA IQESGYAGFL LPVEIYFRNR DEPKRIVYQY DLVLQSTGPP QHHVEVKTHI 120
  121 FEAPSEEFRT KLMRGGGVPV FGANIGAGSL ARTLSPSVGS GETAHSNEMS GVKAKGVPGT 180
  181 ISMNSDLNTG KKHKSRSEDP GKSNAFSALF GPPITKTSVT ANNMAQVPVS KHSPEAKSAA 240
  241 VGGKGVFHEG REKASKDRDK SSGGDKPREK DKKDRHGRDK DRKSSKSGDG KHERDKEKSK 300
  301 KDKSRDKERE REQGSGNTTS ANALTVATSV GTAGGLVKHT ASPKPGKPNE MGAPSPKKTA 360
  361 NDSAAGAVAP TSRSKERDEH KSVKSESKDK ERSSSKKSKK DKKDKDKQRD ESKDKRMPKD 420
  421 ERPGQSDSPA SGNLQSAHLQ QQSQVASTGK ATPTSVGSNS SSSMVSNIGK QKEEATGKHS 480
  481 EKAAESKGDK STSNGNATDT KKSHKHKKKE KSKDKEKERN DRDKDKDKER DKDKLKEREK 540
  541 DKQHVTGSEK SSTVDPSPKL EGASPATEGG APDKTPVSAS ASSGSKKEKH KKSKEKSSGK 600
  601 DEKRQREAVD KQADTKHTGK SQQSQSGQSK TPSNLDLSDM DSAQSAPDLA ATNALAAAAA 660
  661 ATLQHSDSSN SSFPDLPARS SSQQKPTKGN TGSGKETKST VKEHKGKSKQ NDKTLEKNTD 720
  721 KTEKPDKTPD PKVDKSEKSE KEDKKRNRRS SQSSNSGSGA GVTGAFIEPP VKASKKEQGK 780
  781 AAGEKSKSPS LRPPRETNST GTGGGTPNAG AGFLAPPSSS PSNNHSAAVA ASLNNNNNNN 840
  841 NNNTNSNSSH SPGEMTTPGQ LQLPTEYLSE LQELHHKIMT LQDNEELQHV VEMIAATGCY 900
  901 EITHKTFDFD LCKLDRGTVQ RLQEFLATSV S

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..133] Pfam 42.060481 No description for PF03366.7 was found. No confident structure predictions are available.
    2 View Details [134..272] deduced N/A No confident structure predictions are available.
    3 View Details [273..407] deduced N/A No confident structure predictions are available.
    4 View Details [408..510] deduced N/A No confident structure predictions are available.
    5 View Details [511..615] deduced N/A No confident structure predictions are available.
    6 View Details [616..697] deduced N/A No confident structure predictions are available.
    7 View Details [698..931] FFAS03 1.01 No description for 2j63A was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle