YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: pr-set7-PA, pr-s...

General Information:
Name(s) found: FBpp0301702 [FlyBase]
pr-set7-PB / FBpp0082389 [FlyBase]
pr-set7-PA / FBpp0082388 [FlyBase]
Description(s) found:
Found 53 descriptions.
SHOW ALL
  • type=protein; loc=3R:join(10142334..10142589,10142661..10144480); ID=FBpp0301702; name=pr-set7-PD; parent=FBgn0011474,FBtr0309996; dbxref=FlyBase:FBpp0301702,FlyBase_Annotation_IDs:CG3307-PD,REFSEQ:NP_001247100,GB_protein:AFH06418; MD5=157de2b8904725605aacc57a36c3a576; length=691; release=r5.56; species=Dmel; [FlyBase]
  • The gene pr-set7 is referred to in FlyBase by the symbol Dmel\pr-set7 (CG3307, FBgn0011474). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:10141710..10145597. It has the cytological map location 88B3. There is experimental evidence that it has the molecular function</span>: histone methyltransferase activity (H4-K20 specific). There is experimental evidence that it is involved in the biological process</span>: histone methylation; chromosome condensation; histone H4-K20 monomethylation; DNA damage checkpoint. 5 alleles are reported. The phenotypes of these alleles are annotated with: wing margin; eye; dorsal mesothoracic disc; macrochaeta; larval digestive system; condensed chromosome; melanotic mass; ventral thoracic disc; larval cuticle; larval tracheal system. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • The gene pr-set7 is referred to in FlyBase by the symbol Dmel\pr-set7 (CG3307, FBgn0011474). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:10141710..10145597. It has the cytological map location 88B3. There is experimental evidence that it has the molecular function</span>: histone methyltransferase activity (H4-K20 specific). There is experimental evidence that it is involved in the biological process</span>: histone methylation; chromosome condensation; histone H4-K20 monomethylation; DNA damage checkpoint. 5 alleles are reported. The phenotypes of these alleles are annotated with: wing margin; eye; dorsal mesothoracic disc; macrochaeta; larval digestive system; condensed chromosome; melanotic mass; ventral thoracic disc; larval cuticle; larval tracheal system. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 691 amino acids

    Gene Ontology:
    Cellular Component: polytene chromosome [IDA]
    Biological Process: negative regulation of histone acetylation [TAS]
    DNA damage checkpoint [IDA]
    histone H4-K20 monomethylation [IMP]
    chromosome condensation [IDA][IGI]
    histone methylation [IMP][NAS][TAS]
    Molecular Function: histone methyltransferase activity (H4-K20 specific) [IMP][NAS][TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIMVRRRQRP AKEAASSSSG GASSGSGIPV DQALPLNVAG NLLEDQYFAS PKRKDCRLMK  60
   61 VTQNGQLPEA TMMAHNKDNK AGRTIGVPLA TRSQTRTIEN FFKANAAAKD SQKTIHTEEQ 120
  121 LNLGNQELKL DDEELNGQIK LDDEVLKLAD KQINENLPFA DEVDAKAEQK LMDEELQQVV 180
  181 EELLFDGSSR ASSNSPFYQH DMDVMQEIQQ TPEIPHIKKV TEPLEGLGSL ADFQTHRSAL 240
  241 RDSHSSTHSS STDNIFLQEP VLTLDIDRTP TKASSIKINR SFELAGAVFS SPPSVLNACL 300
  301 NGRFNQIVSL NGQKEALDLP HFDLDQHDSS SCDSGVACGL TANTESPAGQ PRRRKPATPH 360
  361 RILCPSPIKT ALKVTGGICK VGSADPLSPR KSPRKLPTTT AAVAACKSRR RLNQPKPQAP 420
  421 YQPQLQKPPS QQQQQQQDDI VVVLDDDDDE GDDEDDVRAL IKAAEERENQ NKAPATANSN 480
  481 KAGMKTMLKP APVKSKTKSK GPTKGQPPLP LAATNGNREM TDFFPVRRSV RKTKTAVKEE 540
  541 WMRGLEQAVL EERCDGLQVR HFMGKGRGVV ADRPFKRNEF VVEYVGDLIS IGEAAEREKR 600
  601 YALDENAGCY MYYFKHKSQQ YCIDATVDTG KLGRLINHSR AGNLMTKVVL IKQRPHLVLL 660
  661 AKDDIEPGEE LTYDYGDRSK ESLLHHPWLA F

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..154] deduced N/A No confident structure predictions are available.
    2 View Details [155..388] MSA 3.244996 View MSA. No confident structure predictions are available.
    3 View Details [389..527] deduced N/A No confident structure predictions are available.
    4 View Details [528..691] PSI-BLAST 46.0 Crystal structure of hSET8 in ternary complex with H4 peptide (16-24) and AdoHcy


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle