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View Structure Prediction Details

Protein: pr-set7-PA, pr-s...
Organism: Drosophila melanogaster
Length: 691 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for pr-set7-PA, pr-s....

Description E-value Query
Range
Subject
Range
SETD8_DROPS - Histone-lysine N-methyltransferase pr-set7 OS=Drosophila pseudoobscura pseudoobscura GN=pr-set7 PE=3...
gi|125775481, gi... - gi|54638698|gb|EAL28100.1| GA17259-PA [Drosophila pseudoobscura], gi|125775481|ref|XP_001358957.1| G...
242.0 [0..3] [691..1]

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Predicted Domain #1
Region A:
Residues: [1-154]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIMVRRRQRP AKEAASSSSG GASSGSGIPV DQALPLNVAG NLLEDQYFAS PKRKDCRLMK  60
   61 VTQNGQLPEA TMMAHNKDNK AGRTIGVPLA TRSQTRTIEN FFKANAAAKD SQKTIHTEEQ 120
  121 LNLGNQELKL DDEELNGQIK LDDEVLKLAD KQIN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [155-388]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENLPFADEVD AKAEQKLMDE ELQQVVEELL FDGSSRASSN SPFYQHDMDV MQEIQQTPEI  60
   61 PHIKKVTEPL EGLGSLADFQ THRSALRDSH SSTHSSSTDN IFLQEPVLTL DIDRTPTKAS 120
  121 SIKINRSFEL AGAVFSSPPS VLNACLNGRF NQIVSLNGQK EALDLPHFDL DQHDSSSCDS 180
  181 GVACGLTANT ESPAGQPRRR KPATPHRILC PSPIKTALKV TGGICKVGSA DPLS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [389-527]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PRKSPRKLPT TTAAVAACKS RRRLNQPKPQ APYQPQLQKP PSQQQQQQQD DIVVVLDDDD  60
   61 DEGDDEDDVR ALIKAAEERE NQNKAPATAN SNKAGMKTML KPAPVKSKTK SKGPTKGQPP 120
  121 LPLAATNGNR EMTDFFPVR

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [528-691]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RSVRKTKTAV KEEWMRGLEQ AVLEERCDGL QVRHFMGKGR GVVADRPFKR NEFVVEYVGD  60
   61 LISIGEAAER EKRYALDENA GCYMYYFKHK SQQYCIDATV DTGKLGRLIN HSRAGNLMTK 120
  121 VVLIKQRPHL VLLAKDDIEP GEELTYDYGD RSKESLLHHP WLAF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 46.0
Match: 1zkkA
Description: Crystal structure of hSET8 in ternary complex with H4 peptide (16-24) and AdoHcy
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle