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Protein Overview: RpII140-PA, FBpp...

General Information:
Name(s) found: FBpp0310926 [FlyBase]
RpII140-PA / FBpp0082353 [FlyBase]
Description(s) found:
Found 29 descriptions.
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  • type=protein; loc=3R:join(9951669..9951690,9951818..9953986,9954062..9954996,9955056..9955460); ID=FBpp0310926; name=RpII140-PB; parent=FBgn0262955,FBtr0344600; dbxref=FlyBase:FBpp0310926,FlyBase_Annotation_IDs:CG3180-PB; MD5=e111e1ececb7182e141885833544dc9b; length=1176; release=r5.56; species=Dmel; [FlyBase]
  • The gene RNA polymerase II 140kD subunit is referred to in FlyBase by the symbol Dmel\RpII140 (CG3180, FBgn0003276). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:9951515..9955548. It has the cytological map location 88A9. Based on sequence similarity, it is predicted to have molecular function</span>: DNA-directed RNA polymerase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: transcription from RNA polymerase II promoter. 63 alleles are reported. The phenotype of these alleles is annotated with: capitellum. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1176 amino acids

    Gene Ontology:
    Cellular Component: DNA-directed RNA polymerase II, core complex [ISS][NAS]
    Biological Process: transcription [IEA]
    transcription from RNA polymerase II promoter [ISS][NAS]
    Molecular Function: DNA binding [IEA]
    DNA-directed RNA polymerase activity [ISS][NAS]
    ribonucleoside binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMYDNEEELY EEENAEEISH ELWQEACWIV INAYFDEKGL VRQQLDSFDE FIQMSVQRIV  60
   61 EDSPAIELQA EAQHTSGEVE TPPRFSLKFE QIYLSKPTHW EKDGSPSPMM PNEARLRNLT 120
  121 YSAPLYVDIT KTKNVEGLDP VETQHQKTFI GKIPIMLRST YCLLSQLTDR DLTELNECPL 180
  181 DPGGYFIING SEKVLIAQEK MATNTVYVFS MKDGKYAFKT EIRSCLEHSS RPTSTLWVNM 240
  241 MARGSQNIKK SAIGQRIIAI LPYIKQEIPI MIVFRALGFV ADRDILEHII YDFDDPEMME 300
  301 MVKPSLDEAF VVQEQNVALN FIGARGARPG VTKDKRIKYA KEILQKEMLP HVGVSDFCET 360
  361 KKAYFLGYMV HRLLLASLGR RELDDRDHYG NKRLDLAGPL LAFLFRGLFK NLMKEVRMYT 420
  421 QKFIDRGKDF NLELAIKTNI ITDGLRYSLA TGNWGDQKKA HQARAGVSQV LNRLTFASTL 480
  481 SHLRRVNSPI GRDGKLAKPR QLHNTLWGML CPAETPEGAA VGLVKNLALM AYISVGSQPS 540
  541 PILEFLEEWS MENLEEIAPS AIADATKIFV NGCWVGIHRD PEQLMATLRK LRRQMDIIVS 600
  601 EVSMIRDIRD REIRIYTDAG RICRPLLIVE NGSLLLKKTH VEMLKERDYN NYSWQVLVAS 660
  661 GVVEYIDTLE EETVMIAMSP YDLKQDKDYA YCTTYTHCEI HPAMILGVCA SIIPFPDHNQ 720
  721 SPRNTYQSAM GKQAMGVYIT NFHVRMDTLA HVLYYPMKPL VTTRSMEYLR FRELPAGINS 780
  781 IVAILCYTGY NQEDSVILNA SAVERGFFRS VFYRSYKDSE NKRVGDQEEN FEKPHRGTCQ 840
  841 GMRNAHYDKL DDDGIIAPGI RVSGDDVVIG KTITLPENDD ELDSNTKRFS KRDASTFLRN 900
  901 SETGIVDQVM LTLNSEGYKF CKIRVRSVRI PQIGDKFASR HGQKGTCGIQ YRQEDMAFTC 960
  961 EGLAPDIIIN PHAIPSRMTI GHLIECLQGK LGSNKGEIGD ATPFNDAVNV QKISTFLQEY1020
 1021 GYHLRGNEVM YNGHTGRKIN AQVFLGPTYY QRLKHMVDDK IHSRARGPVQ ILVRQPMEGR1080
 1081 ARDGGLRFGE MERDCQISHG AAQFLRERLF EVSDPYRVHI CNFCGLIAIA NLRNNTFECK1140
 1141 GCKNKTQISQ VRLPYAAKLL FQELMSMNIA PRLMVT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..1176] PSI-BLAST 1000.0 RBP2


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle