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Protein Overview: Ipp-PA

General Information:
Name(s) found: Ipp-PA / FBpp0082328 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene Inositol polyphosphate 1-phosphatase is referred to in FlyBase by the symbol Dmel\Ipp (CG3028, FBgn0016672). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:9784473..9786196. It has the cytological map location 88A3. There is experimental evidence that it has the molecular function</span>: inositol-1,4-bisphosphate 1-phosphatase activity. There is experimental evidence that it is involved in the biological process</span>: synaptic transmission; inositol phosphate dephosphorylation. 6 alleles are reported. The phenotype of these alleles is annotated with: synapse. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 375 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: synaptic transmission [IMP]
    inositol phosphate dephosphorylation [IDA][IMP]
    Molecular Function: inositol-1,4-bisphosphate 1-phosphatase activity [IDA][IMP][ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGVEEQASL LRVLINCAEK AANIARICRS NEQLLALLVQ EKIGSEANER FEHDFKTLAD  60
   61 VLIQETIKHE VGALFPAMKD AILGEESPNF TNQLGESVTI AVGATEEDTA ACLQAVLSGH 120
  121 EDAASALATE VHRDVSFSSE KLGEIAQLPD ELDYGNLGIW IDPIDATAEY ISGDTMFTDF 180
  181 PGITSTGLDC VTVLIGVYER DTGVPVMGVV AQPFGEKLEE NVYSSSMFWG VCLPTVRAHN 240
  241 CDFEARDENR RLGIFSSSEQ SDILQRFLDL GYEFAFSAGA GHKALKVITH EVDVYLLSKG 300
  301 STFKWDTCAP QAILRALGGD VLDYAASVAE QKAVPLKYLI EDAEADADWK RNAGGIISVR 360
  361 NVDVVDELLA KLAEQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..375] PSI-BLAST 49.39794 CRYSTAL STRUCTURE OF INOSITOL POLYPHOSPHATE 1-PHOSPHATASE AT 2.3 ANGSTROMS RESOLUTION

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • phosphatase activity
    		•  6.6999804091595 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  6.49576549923618 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  5.67797126172872 bayes_pls_golite062009
  • hydrolase activity
    		•  4.25960462382519 bayes_pls_golite062009
  • inositol-1(or 4)-monophosphatase activity
    		•  3.37597803693973 bayes_pls_golite062009
  • inositol or phosphatidylinositol phosphatase activity
    		•  3.2519333355725 bayes_pls_golite062009
  • catalytic activity
    		•  2.13229228332707 bayes_pls_golite062009
  • carbohydrate phosphatase activity
    		•  1.70818382327628 bayes_pls_golite062009
  • fructose 1,6-bisphosphate 1-phosphatase activity
    		•  1.61382250100271 bayes_pls_golite062009
  • binding
    		•  0.629152924370114 bayes_pls_golite062009
  • protein binding
    		•  0.0306489545337429 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle