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Protein Overview: wntD-PA

General Information:
Name(s) found: wntD-PA / FBpp0082243 [FlyBase]
Description(s) found:
Found 23 descriptions.
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  • The gene wnt inhibitor of Dorsal is referred to in FlyBase by the symbol Dmel\wntD (CG8458, FBgn0038134). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:9117774..9118920. It has the cytological map location 87E4. It is reported to have molecular function</span>: frizzled binding. There is experimental evidence that it is involved in the biological process</span>: ventral furrow formation; defense response to Gram-positive bacterium; regulation of embryonic development. 10 alleles are reported. The phenotypes of these alleles are annotated with: mesoderm; ventral furrow. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 309 amino acids

    Gene Ontology:
    Cellular Component: extracellular region [IEA]
    proteinaceous extracellular matrix [NAS]
    Biological Process: ventral furrow formation [IMP]
    Wnt receptor signaling pathway, calcium modulating pathway [IEA]
    regulation of embryonic development [IMP]
    Wnt receptor signaling pathway [NAS]
    defense response to Gram-positive bacterium [IGI][IMP]
    Molecular Function: frizzled binding [NAS]
    signal transducer activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIFAITFFMG ITSTLAAVLE PMSYYQYTQF QAPLSWEDIT GKGLKQALDS CQQSFQWQRW  60
   61 NCPSQDFVQK NSKPEENSPN REDVYVAAIS MAAIVHTLTK DCANGVIAGC GCTENALNVP 120
  121 CAHEPTKALE QYEKHFGSGS GAIGHNRRVV GALLQRSLEQ ECRCKQPGAV QGECQEEECV 180
  181 AVLKPFEAIA QDLLQMYDDA IQLEGASSNL KIMWQNIPLD SLVFMQDSPN YCERDATGLW 240
  241 KGTRGRQCSK DGSGSLEERL SCQQLCRVCG YRVRSQHVRT ERRCNCKLVW GFRLQCDVCV 300
  301 QLERQYSCY

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..166] MSA 8.171981 View MSA. No confident structure predictions are available.
    2 View Details [167..309] MSA 46.208986 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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