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Protein Overview: CG8449-PA

General Information:
Name(s) found: CG8449-PA / FBpp0082246 [FlyBase]
Description(s) found:
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  • gi|78214279|gb|ABB36454.1| GH10459p [Drosophila melanogaster] [NCBI NR]
  • gi|7299738|gb|AAF54919.1| CG8449 [Drosophila melanogaster] [NCBI NR]
  • gi|24646498|ref|NP_731780.1| CG8449 [Drosophila melanogaster] [NCBI NR]
  • This gene is referred to in FlyBase by the symbol Dmel\CG8449 (CG8449, FBgn0038129). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:9094859..9097748. It has the cytological map location 87E3. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: Rab GTPase activator activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: regulation of Rab GTPase activity. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG8449-PA translation from_gene[CG8449 CG8449 FBgn0038129] seq_release:3 mol_weight=74338 cds_boundaries:(3R:9,095,064..9,097,582[-]) aa_length:654 transcript_info:[CG8449-RA seq_release:3] gene_info:[gene symbol:CG8449 FBgn0038129 gene_boundaries:(3R [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9VFX6) CG8449 protein [DrosMelano7227.FASTAC.txt]
  • (AE003699) CG8449 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG8449-PA [Drosophila melanogaster]gi|24646498|ref|NP_731780.1| CG8449-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:complement(9095042..9095551,9095800..9096152,9096214..9096356,9096489..9096631,9096691..9096787,9096845..9097563); ID=FBpp0082246; name=CG8449-PA; parent=FBgn0038129,FBtr0082778; dbxref=FlyBase:FBpp0082246,FlyBase_Annotation_IDs:CG844 [fly-100309-contam.fasta]
  • CG8449-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • GH10459p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:complement(9095042..9095551,9095800..9096152,9096214..9096356,9096489..9096631,9096691..9096787,9096845..9097563); ID=FBpp0082246; name=CG8449-PA; parent=FBgn0038129,FBtr0082778; dbxref=FlyBase:FBpp0082246,FlyBase_Annotation_IDs:CG8449-PA,GB_protein:AAF54919.1,REFSEQ:NP_731780,GB_protein:AAF54919; MD5=e38a6e086f1045b243e25bf9d4965645; length=654; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:complement(9095042..9095551,9095800..9096152,9096214..9096356,9096489..9096631,9096691..9096787,9096845..9097563); ID=FBpp0082246; name=CG8449-PA; parent=FBgn0038129,FBtr0082778; dbxref=FlyBase:FBpp0082246,FlyBase_Annotation_IDs:CG8449-PA,GB_protein:AAF54919.1,REFSEQ:NP_731780,GB_protein:AAF54919; MD5=e38a6e086f1045b243e25bf9d4965645; length=654; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • CG8449 OS=Drosophila melanogaster GN=CG8449 PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3R:complement(9095042..9095551,9095800..9096152,9096214..9096356,9096489..9096631,9096691..9096787,9096845..9097563); ID=FBpp0082246; name=CG8449-PA; parent=FBgn0038129,FBtr0082778; dbxref=FlyBase:FBpp0082246,FlyBase_Annotation_IDs:CG8449-PA,GB_protein:AAF54919.1,REFSEQ:NP_731780,GB_protein:AAF54919,FlyMine:FBpp0082246,modMine:FBpp0082246; MD5=e38a6e086f1045b243e25bf9d4965645; length=654; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • CG8449 OS=Drosophila melanogaster GN=CG8449 PE=2 SV=1 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta]
  • type=protein; loc=3R:complement(join(13271123..13271841,13270969..13271065,13270767..13270909,13270492..13270634,13270078..13270430,13269320..13269829)); ID=FBpp0082246; name=CG8449-PA; parent=FBgn0038129,FBtr0082778; dbxref=FlyBase:FBpp0082246,FlyBase_Annotation_IDs:CG8449-PA,GB_protein:AAF54919.1,REFSEQ:NP_731780,GB_protein:AAF54919,FlyMine:FBpp0082246,modMine:FBpp0082246; MD5=e38a6e086f1045b243e25bf9d4965645; length=654; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:complement(join(13271123..13271841,13270969..13271065,13270767..13270909,13270492..13270634,13270078..13270430,13269320..13269829)); ID=FBpp0082246; name=CG8449-PA; parent=FBgn0038129,FBtr0082778; dbxref=FlyBase:FBpp0082246,FlyBase_Annotation_IDs:CG8449-PA,GB_protein:AAF54919.1,REFSEQ:NP_731780,GB_protein:AAF54919,FlyMine:FBpp0082246,modMine:FBpp0082246; MD5=e38a6e086f1045b243e25bf9d4965645; length=654; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0082246 type=protein; loc=3R:complement(join(13271123..13271841,13270969..13271065,13270767..13270909,13270492..13270634,13270078..13270430,13269320..13269829)); ID=FBpp0082246; name=CG8449-PA; parent=FBgn0038129,FBtr0082778; dbxref=FlyBase:FBpp0082246,FlyBase_Annotation_IDs:CG8449-PA,GB_protein:AAF54919.1,REFSEQ:NP_731780,GB_protein:AAF54919,FlyMine:FBpp0082246,modMine:FBpp0082246; MD5=e38a6e086f1045b243e25bf9d4965645; length=654; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3R:complement(join(13271123..13271841,13270969..13271065,13270767..13270909,13270492..13270634,13270078..13270430,13269320..13269829)); ID=FBpp0082246; name=TBC1D5-PA; parent=FBgn0038129,FBtr0082778; dbxref=FlyBase:FBpp0082246,FlyBase_Annotation_IDs:CG8449-PA,GB_protein:AAF54919.1,REFSEQ:NP_731780,GB_protein:AAF54919,UniProt/TrEMBL:Q9VFX6,FlyMine:FBpp0082246,modMine:FBpp0082246; MD5=e38a6e086f1045b243e25bf9d4965645; length=654; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 654 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEA]
    Biological Process: regulation of Rab GTPase activity [IEA]
    Molecular Function: Rab GTPase activator activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTVWGIEAIT LNGSSARESL EHLPGNGAIR VIPEAGAMNS VERYRQEWQV LLENLDADPE  60
   61 SLRQSAFAGD LKMSKFRSVH WALLLRVLTS EHRSWTSQRL QQRVRYDKFR ADYVRNPHQL 120
  121 AVDCNDDPLS QSTQSVWNQY FSDQDLFAVI RQDVVRTFPG VDFFRKPLVQ NAMVNILFYY 180
  181 AREHPYMCYR QGMHEILAPI IFVVYSDHQS LLHFSELAKT DINPTLLDVL DPAYLEADTY 240
  241 SLFSRLMASV ESYYRVSNLV STPGGHIEQR AESPGDNETS TEAEVIGQLN FIRDKILAKQ 300
  301 DQHLHHYLQK MEIPLHIFGI RWLRLLFGRE FMLLDLLLLW DAIFADSDRF DLPNYILVAM 360
  361 LVHIRDKLLL SDYTTSLTYL MRYPNNVDVH LVLRHALFML NPKQFEYPPN AFTCVSFANS 420
  421 SADKDVPPPA GQRPRTNSEN SSMATSGSQI DRQITFMQER NAADSSALAK LQDTHRVAMD 480
  481 GYLENSPELL RLELKNAQTV IKIARSKLQS YLSTVRHHVG KQANGSEELG RTLDGIEELC 540
  541 SFLDVKFMFP LHQRSAPIDQ ALEANEQKQL NTVSKPPKPT ASSTPANAPA ALSATGGYQM 600
  601 PENAFMHSSM RRLLGELREI ELSTITSDEK PGNAVVQNGL PAAEPQQRHR NESS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..414] PSI-BLAST 50.69897 No description for 2qfzA was found.
    2 View Details [415..654] PSI-BLAST 14.09691 Heavy meromyosin subfragment


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle