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Protein Overview: ry-PA

General Information:
Name(s) found: ry-PA / FBpp0082172 [FlyBase]
Description(s) found:
Found 23 descriptions.
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  • The gene rosy is referred to in FlyBase by the symbol Dmel\ry (CG7642, FBgn0003308). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:8858259..8863748. It has the cytological map location 87D9. It is reported to have molecular function</span>: xanthine dehydrogenase activity. There is experimental evidence that it is involved in the biological process</span>: pyrimidine base metabolic process; determination of adult lifespan; arginine metabolic process; tryptophan metabolic process; glycerophospholipid metabolic process; purine base metabolic process. 354 alleles are reported. The phenotypes of these alleles are annotated with: Malpighian tubule; pigment cell. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1335 amino acids

    Gene Ontology:
    Cellular Component: peroxisome [NAS]
    Biological Process: pyrimidine base metabolic process [IMP]
    arginine metabolic process [IMP]
    determination of adult lifespan [IMP]
    oxidation reduction [IEA]
    purine base metabolic process [IMP]
    glycerophospholipid metabolic process [IMP]
    tryptophan metabolic process [IMP]
    compound eye pigmentation [TAS]
    Molecular Function: xanthine dehydrogenase activity [IEA][NAS][TAS]
    xanthine oxidase activity [IEA]
    FAD binding [IEA]
    iron ion binding [IEA]
    electron carrier activity [IEA]
    iron-sulfur cluster binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNSVLVFFV NGKKVTEVSP DPECTLLTFL REKLRLCGTK LGCAEGGCGA CTVMVSRLDR  60
   61 RANKIRHLAV NACLTPVCSM HGCAVTTVEG IGSTKTRLHP VQERLAKAHG SQCGFCTPGI 120
  121 VMSMYALLRN AEQPSMRDLE VAFQGNLCRC TGYRPILEGY KTFTKEFACG MGEKCCKVSG 180
  181 KGCGTDAETD DKLFERSEFQ PLDPSQEPIF PPELQLSDAF DSQSLIFSSD RVTWYRPTNL 240
  241 EELLQLKAKH PAAKLVVGNT EVGVEVKFKH FLYPHLINPT QVKELLEIKE NQDGIYFGAA 300
  301 VSLMEIDALL RQRIEQLPES ETRLFQCTVD MLHYFAGKQI RNVACLGGNI MTGSPISDMN 360
  361 PVLSAAGAQL EVASFVDGKL QKRSVHMGTG FFTGYRRNVI EAHEVLLGIH FRKTTPDQYI 420
  421 VAFKQARRRD DDIAIVNAAI NVRFEEKSNI VAEISMAFGG MAPTTVLAPR TSQLMVGQEW 480
  481 SHQLVERVAE SLCTELPLAA SAPGGMIAYR RALVVSLFFK AYLAISLKLS KSGITSSDAL 540
  541 PSEERSGAET FHTPVLKSAQ LFERVCSDQP ICDPIGRPKV HAAALKQATG EAIYTDDIPR 600
  601 MDGEVYLAFV LSTKPRAKIT KLDASEALAL DGVHQFFCYK DLTEHENEVG PVFHDEHVFA 660
  661 AGEVHCYGQI VGAIAADNKA LAQRAARLVK VEYEELSPVI VTIEQAIEHK SYFPDYPRFV 720
  721 TKGNVEEALA QADHTFEGTC RMGGQEHFYL ETHAALAVPR DSDELELFCS TQHPSEVQKL 780
  781 VAHVTALPAH RVVCRAKRLG GGFGGKESRG ISVALPVALA AYRMGRPVRC MLDRDEDMLI 840
  841 TGTRHPFLFK YKVGFTKEGL ITACDIECYN NAGWSMDLSF SVLERAMFHF ENCYRIPNVR 900
  901 VGGWVCKTNL PSNTAFRGFG GPQGMYAGEH IIRDVARIVG RDVVDVMRLN FYKTGDYTHY 960
  961 HQQLEHFPIE RCLEDCLKQS RYDEKRQEIA RFNRENRWRK RGMAVVPTKY GIAFGVMHLN1020
 1021 QAGSLINIYG DGSVLLSHGG VEIGQGLNTK MIQCAARALG IPSELIHISE TATDKVPNTS1080
 1081 PTAASVGSDL NGMAVLDACE KLNKRLAPIK EALPGGTWKE WINKAYFDRV SLSATGFYAM1140
 1141 PGIGYHPETN PNARTYSYYT NGVGVTVVEI DCLTGDHQVL STDIVMDIGS SLNPAIDIGQ1200
 1201 IEGAFMQGYG LFTLEELMYS PQGMLYSRGP GMYKLPGFAD IPGEFNVSLL TGAPNPRAVY1260
 1261 SSKAVGEPPL FIGSSAFFAI KEAIAAARED QGLSGDFPLE APSTSARIRI ACQDKFTELL1320
 1321 EIPEPGSFTP WNIVP

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..1335] PSI-BLAST 1000.0 No description for 2ckjA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.70

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle