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Protein Overview: Spc25-PA

General Information:
Name(s) found: Spc25-PA / FBpp0082158 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene Spc25 is referred to in FlyBase by the symbol Dmel\Spc25 (CG7242, FBgn0087021). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:8787474..8788975. It has the cytological map location 87D5. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: mitotic metaphase plate congression; chromosome segregation; mitotic spindle organization. 12 alleles are reported. The phenotypes of these alleles are annotated with: metaphase; condensed nuclear chromosome; macrochaeta; dorsocentral bristle; spindle; imaginal disc; larval brain; nucleus. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 222 amino acids

    Gene Ontology:
    Cellular Component: Ndc80 complex [IDA][ISS]
    kinetochore [IDA]
    Biological Process: mitotic spindle organization [IMP]
    chromosome segregation [IMP]
    mitotic metaphase plate congression [IMP]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAIIMTESSY ERRVKALYEK QIHMEALEAK FIKKVFKFNS NLLDVKEAAS RHQRKVGKLQ  60
   61 KVLMERREEL DKRVSFIEEL DRELEATKLH NLAMKDWFKQ QKMLAKQRKN EIMESIHTLS 120
  121 KTTRTYINQE ALPARVKGVT VLRGDKRDQL IPFDLKATDV EGLDSLCQHL ESLNVDVAQW 180
  181 QQLISLAMDM AMESRAPTTP PKEADNCKSI IEIDLTSPMS HT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..222] FFAS03 1.59 Ribonuclease domain of colicin E3; Colicin E3 translocation domain; Colicin E3 receptor domain


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle