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Protein Overview: GstD8-PA

General Information:
Name(s) found: GstD8-PA / FBpp0082047 [FlyBase]
Description(s) found:
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  • gi|92110008|gb|ABE73328.1| IP02538p [Drosophila melanogaster] [NCBI NR]
  • gi|7299608|gb|AAF54793.1| glutathione S transferase D8 [Drosophila melanogaster] [NCBI NR]
  • gi|17864598|ref|NP_524916.1| glutathione S transferase D8 [Drosophila melanogaster] [NCBI NR]
  • The gene Glutathione S transferase D8 is referred to in FlyBase by the symbol Dmel\GstD8 (CG4421, FBgn0010044). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:8205745..8206537. It has the cytological map location 87B8. Based on sequence similarity, it is predicted to have molecular function</span>: glutathione transferase activity. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG4421-PA translation from_gene[CG4421 GstD8 FBgn0010044] seq_release:3 mol_weight=24180 cds_boundaries:(3R:8,205,777..8,206,412[+]) aa_length:212 transcript_info:[CG4421-RA seq_release:3] gene_info:[gene symbol:GstD8 FBgn0010044 gene_boundaries:(3R:8 [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9VG92) CG4421 protein [DrosMelano7227.FASTAC.txt]
  • (AE003695) GstD27 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG4421-PA [Drosophila melanogaster]gi|17864598|ref|NP_524916.1| CG4421-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:8205758..8206396; ID=FBpp0082047; name=GstD8-PA; parent=FBgn0010044,FBtr0082575; dbxref=FlyBase:FBpp0082047,FlyBase_Annotation_IDs:CG4421-PA,GB_protein:AAF54793.1,REFSEQ:NP_524916,GB_protein:AAF54793; MD5=e5668ab3b0a85dcc4c4480e9406e3 [fly-100309-contam.fasta]
  • CG4421-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • IP02538p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Glutathione S transferase D8 CG4421-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:8205758..8206396; ID=FBpp0082047; name=GstD8-PA; parent=FBgn0010044,FBtr0082575; dbxref=FlyBase:FBpp0082047,FlyBase_Annotation_IDs:CG4421-PA,GB_protein:AAF54793.1,REFSEQ:NP_524916,GB_protein:AAF54793; MD5=e5668ab3b0a85dcc4c4480e9406e3214; length=212; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:8205758..8206396; ID=FBpp0082047; name=GstD8-PA; parent=FBgn0010044,FBtr0082575; dbxref=FlyBase:FBpp0082047,FlyBase_Annotation_IDs:CG4421-PA,GB_protein:AAF54793.1,REFSEQ:NP_524916,GB_protein:AAF54793; MD5=e5668ab3b0a85dcc4c4480e9406e3214; length=212; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Glutathione S transferase D8 OS=Drosophila melanogaster GN=GstD8 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3R:8205758..8206396; ID=FBpp0082047; name=GstD8-PA; parent=FBgn0010044,FBtr0082575; dbxref=FlyBase:FBpp0082047,FlyBase_Annotation_IDs:CG4421-PA,GB_protein:AAF54793.1,REFSEQ:NP_524916,GB_protein:AAF54793,FlyMine:FBpp0082047,modMine:FBpp0082047; MD5=e5668ab3b0a85dcc4c4480e9406e3214; length=212; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:12380036..12380674; ID=FBpp0082047; name=GstD8-PA; parent=FBgn0010044,FBtr0082575; dbxref=FlyBase:FBpp0082047,FlyBase_Annotation_IDs:CG4421-PA,GB_protein:AAF54793.1,REFSEQ:NP_524916,GB_protein:AAF54793,FlyMine:FBpp0082047,modMine:FBpp0082047; MD5=e5668ab3b0a85dcc4c4480e9406e3214; length=212; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:12380036..12380674; ID=FBpp0082047; name=GstD8-PA; parent=FBgn0010044,FBtr0082575; dbxref=FlyBase:FBpp0082047,FlyBase_Annotation_IDs:CG4421-PA,GB_protein:AAF54793.1,REFSEQ:NP_524916,GB_protein:AAF54793,FlyMine:FBpp0082047,modMine:FBpp0082047; MD5=e5668ab3b0a85dcc4c4480e9406e3214; length=212; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0082047 type=protein; loc=3R:12380036..12380674; ID=FBpp0082047; name=GstD8-PA; parent=FBgn0010044,FBtr0082575; dbxref=FlyBase:FBpp0082047,FlyBase_Annotation_IDs:CG4421-PA,GB_protein:AAF54793.1,REFSEQ:NP_524916,GB_protein:AAF54793,FlyMine:FBpp0082047,modMine:FBpp0082047; MD5=e5668ab3b0a85dcc4c4480e9406e3214; length=212; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3R:12380036..12380674; ID=FBpp0082047; name=GstD8-PA; parent=FBgn0010044,FBtr0082575; dbxref=FlyBase:FBpp0082047,FlyBase_Annotation_IDs:CG4421-PA,GB_protein:AAF54793.1,REFSEQ:NP_524916,GB_protein:AAF54793,UniProt/TrEMBL:Q9VG92,FlyMine:FBpp0082047,modMine:FBpp0082047; MD5=e5668ab3b0a85dcc4c4480e9406e3214; length=212; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 212 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: glutathione peroxidase activity [TAS]
    glutathione transferase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDFYYHPCSA PCRSVIMTAK ALGVDLNMKL LKVMDGEQLK PEFVKLNPQH CIPTLVDDGF  60
   61 SIWESRAILI YLVEKYGADD SLYPSDPQKK AVVNQRLYFD MGTLFQSFVE AIYPQIRNNH 120
  121 PADPEAMQKV DSAFGHLDTF LEDQEYVAGD CLTIADIALL ASVSTFEVVD FDIAQYPNVA 180
  181 RWYENAKEVT PGWEENWDGV QLIKKLVQER NE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..212] PSI-BLAST 46.0 Class delta GST

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • glutathione transferase activity
    		•  3.95712498751783 bayes_pls_golite062009
  • glutathione binding
    		•  3.1027755387739 bayes_pls_golite062009
  • transferase activity, transferring alkyl or aryl (other than methyl) groups
    		•  1.08486797497934 bayes_pls_golite062009
  • catalytic activity
    		•  0.963623964325467 bayes_pls_golite062009
  • selenium binding
    		•  0.703224862997071 bayes_pls_golite062009
  • binding
    		•  0.690808321529132 bayes_pls_golite062009
  • peroxiredoxin activity
    		•  0.366096607480921 bayes_pls_golite062009
  • protein binding
    		•  0.356637551752136 bayes_pls_golite062009
  • thioredoxin peroxidase activity
    		•  0.163136748643487 bayes_pls_golite062009
  • glutathione peroxidase activity
    		•  0.0539815835450801 bayes_pls_golite062009
  • receptor binding
    		•  0.0226227421058591 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle