YRC Public Data Repository - Protein Structure Prediction

Protein:	GstD8-PA
Organism:	Drosophila melanogaster
Length:	212 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GstD8-PA.

Description	E-value	Query Range	Subject Range
GST1C_ANOGA - Glutathione S-transferase 1, isoform C OS=Anopheles gambiae GN=GstD1 PE=1 SV=2 gi\|31208165, gi\|... - gi\|31208165\|ref\|XP_313049.1\| glutathione transferase (AGAP004164-PA) [Anopheles gambiae str. PEST], ...	181.0	[0..1]	[209..1]
gi\|22218856, gi\|... - gi\|22218860\|pdb\|1JLV\|F Chain F, Anopheles Dirus Species B Glutathione S-Transferases 1-3, gi\|2221885... gi\|11596150 - gi\|11596150\|gb\|AAG38505.1\| glutathione transferase GST1-3 [Anopheles dirus]	181.0	[0..1]	[209..1]
gi\|84975, gi\|242503 - pir\|\|JQ1378 glutathione transferase (EC 2.5.1.18) D27 - fruit fly (Drosophila melanogaster), gi\|242...	180.0	[0..1]	[212..1]
GSTT5_ANOGA, GTT... - (Q93112) Glutathione S-transferase 1-5 (EC 2.5.1.18) (GST class-theta), (Q93112) Glutathione S-trans...	179.0	[0..1]	[209..1]
GSTT1_MUSDO - Glutathione S-transferase 1 OS=Musca domestica GN=Gst1 PE=2 SV=1	179.0	[0..1]	[207..1]
gi\|54637756, gi\|... - gi\|54637756\|gb\|EAL27158.1\| GA18171 [Drosophila pseudoobscura pseudoobscura], gi\|125773525\|ref\|XP_001... gi\|54637756\|gb\|E... - GA18171-PA [Drosophila pseudoobscura], GA18171 [Drosophila pseudoobscura pseudoobscura]	176.0	[0..1]	[212..1]

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Predicted Domain #1

Region A:
Residues: [1-212]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDFYYHPCSA PCRSVIMTAK ALGVDLNMKL LKVMDGEQLK PEFVKLNPQH CIPTLVDDGF  60
   61 SIWESRAILI YLVEKYGADD SLYPSDPQKK AVVNQRLYFD MGTLFQSFVE AIYPQIRNNH 120
  121 PADPEAMQKV DSAFGHLDTF LEDQEYVAGD CLTIADIALL ASVSTFEVVD FDIAQYPNVA 180
  181 RWYENAKEVT PGWEENWDGV QLIKKLVQER NE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	46.0
Match:	1jlvA
Description:	Class delta GST
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
glutathione transferase activity	3.95712498751783	bayes_pls_golite062009
glutathione binding	3.1027755387739	bayes_pls_golite062009
transferase activity, transferring alkyl or aryl (other than methyl) groups	1.08486797497934	bayes_pls_golite062009
catalytic activity	0.963623964325467	bayes_pls_golite062009
selenium binding	0.703224862997071	bayes_pls_golite062009
binding	0.690808321529132	bayes_pls_golite062009
peroxiredoxin activity	0.366096607480921	bayes_pls_golite062009
protein binding	0.356637551752136	bayes_pls_golite062009
thioredoxin peroxidase activity	0.163136748643487	bayes_pls_golite062009
glutathione peroxidase activity	0.0539815835450801	bayes_pls_golite062009
receptor binding	0.0226227421058591	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: