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Protein Overview: mfas-PJ

General Information:
Name(s) found: mfas-PJ / FBpp0081972 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene midline fasciclin is referred to in FlyBase by the symbol Dmel\mfas (CG3359, FBgn0260745). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:7810584..7819037. It has the cytological map location 87A7-87A4. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: axonogenesis. 8 alleles are reported. No phenotypic data is available. It has 15 annotated transcripts and 15 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 905 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [NAS]
    Biological Process: axonogenesis [IMP]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRLWACLLL LGSIQIQAVP FYGDSSSEEV AEFDDSSDST HESSDNSSFM PHLTHPLPAH  60
   61 RNLFAPLPFA PLAPLEPQDP LHAQASQRMA SVWNGPAPLA PQLHSSHLLP LFSSGYDTEF 120
  121 VPLEHQQQPQ GRQETAATVP AQTPSGVEQK PFNVDTITTD VNSPNPAIFF QQSFPFFGNE 180
  181 FFNSFGGFGF GAAQEPWWKG PNVCTEKEED ETVASETEAE ETVDTFGQER DGVTNVVRSP 240
  241 LFGQFQFSVN SCAEKPNKHV CTKIVNQNGK KKTLTLTRQC CYGYGRPRNA DFTTPCEKID 300
  301 IKDVEATASD MGAKQFLESA RTAGELADML GAGSGKKVTL FVPNDAAFME YRGHHQQENN 360
  361 VEDAKAEASK PSIYKLHAVL GEVQLEDVPN EKLLQTELPD QKIRINSYQL PAALGLEPYR 420
  421 FAANCVPIEK HDKLSEQALV HTLGGVLKPL TKNLMDIIRE RADMSIMRTV LEKTNLSAML 480
  481 EDDKPVTIFV PTDAAFDKLE PHLRRALKEG RGCASNILKN HLLDLTFCSL ATVPGAKTTA 540
  541 YNLLGEPLLL NRTHRAANQT GPTPIYINNL AKIIDADIMG TNGVLHVIDT ILPTESALPM 600
  601 TSLMSQKNLT IFQRLLEASG YDDQFDDLDN VTIFAPTDKA LQNTEWARML KEQPELLNHN 660
  661 LDLLEFLNYH VVKPMIKTCD LSEKSLPTVA GSSVRLNLYS THALFSDVMN RATVNCARLV 720
  721 HFDDESCGSV LHQVDRALAP PKNNMLKLLE ANPNYSKFLE LVRKANLTQL LSNDSRSLTL 780
  781 LVPKNDIFEE LNESGEGSKP ADPMALVKTH IVEDVVCCAG IIPTNWPFVR SIESISGQHL 840
  841 RITRDRRPKI ENAGVTKCDV VATNGILHEI NDIIVPRPQR QQQQRPQLIP PGAGYQPQGD 900
  901 FDVFF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..77] deduced N/A No confident structure predictions are available.
    2 View Details [78..380] PSI-BLAST 4.69897 Type 1 insulin-like growth factor receptor extracellular domain; Type 1 insulin-like growth factor receptor Cys-rich domain
    3 View Details [381..606] FFAS03 5.85 Fasciclin I
    4 View Details [607..905] PSI-BLAST 42.69897 Fasciclin I

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • growth factor binding
    		•  4.69491298348348 bayes_pls_golite062009
  • extracellular matrix structural constituent
    		•  4.44612590443184 bayes_pls_golite062009
  • insulin-like growth factor binding
    		•  4.02348040390921 bayes_pls_golite062009
  • insulin-like growth factor I binding
    		•  3.71525343314197 bayes_pls_golite062009
  • binding
    		•  2.20806191972252 bayes_pls_golite062009
  • protein binding
    		•  1.73992312316472 bayes_pls_golite062009
  • receptor binding
    		•  1.71462229979093 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  1.37184133178431 bayes_pls_golite062009
  • insulin-like growth factor II binding
    		•  0.992669332214511 bayes_pls_golite062009
  • extracellular matrix binding
    		•  0.907118880836251 bayes_pls_golite062009
  • polysaccharide binding
    		•  0.69382733754772 bayes_pls_golite062009
  • pattern binding
    		•  0.499692374055569 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.343717562511172 bayes_pls_golite062009
  • protein tyrosine phosphatase activator activity
    		•  0.28979948676897 bayes_pls_golite062009
  • G-protein coupled receptor activity
    		•  0.131191540468541 bayes_pls_golite062009
  • glycoprotein binding
    		•  0.1030670765537 bayes_pls_golite062009
  • collagen binding
    		•  0.085405748322021 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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