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Protein Overview: mfas-PH, mfas-PN

General Information:
Name(s) found: mfas-PN / FBpp0081975 [FlyBase]
mfas-PH / FBpp0081970 [FlyBase]
Description(s) found:
Found 32 descriptions.
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  • The gene midline fasciclin is referred to in FlyBase by the symbol Dmel\mfas (CG3359, FBgn0260745). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:7810584..7819037. It has the cytological map location 87A7-87A4. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: axonogenesis. 8 alleles are reported. No phenotypic data is available. It has 15 annotated transcripts and 15 annotated polypeptides. [FlyBase]
  • The gene midline fasciclin is referred to in FlyBase by the symbol Dmel\mfas (CG3359, FBgn0260745). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:7810584..7819037. It has the cytological map location 87A7-87A4. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: axonogenesis. 8 alleles are reported. No phenotypic data is available. It has 15 annotated transcripts and 15 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 815 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [NAS]
    Biological Process: axonogenesis [IMP]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRLWACLLL LGSIQIQAVP FYGDGYDTEF VPLEHQQQPQ GRQETAATVP AQTPSGVEQK  60
   61 PFNVDTITTD VNSPNPAIFF QQSFPFFGNE FFNSFGGFGF GAAQEPWWKG PNVCTEKEED 120
  121 ETVASETEAE ETVDTFGQER DGVTNVVRSP LFGQFQFSVN SCAEKPNKHV CTKIVNQNGK 180
  181 KKTLTLTRQC CYGYGRPRNA DFTTPCEKID IKDVEATASD MGAKQFLESA RTAGELADML 240
  241 GAGSGKKVTL FVPNDAAFME YRGHHQQENN VEDAKAEASK PSIYKLHAVL GEVQLEDVPN 300
  301 EKLLQTELPD QKIRINSYQL PAALGLEPYR FAANCVPIEK HDKLSEQALV HTLGGVLKPL 360
  361 TKNLMDIIRE RADMSIMRTV LEKTNLSAML EDDKPVTIFV PTDAAFDKLE PHLRRALKEG 420
  421 RGCASNILKN HLLDLTFCSL ATVPGAKTTA YNLLGEPLLL NRTHRAANQT GPTPIYINNL 480
  481 AKIIDADIMG TNGVLHVIDT ILPTESALPM TSLMSQKNLT IFQRLLEASG YDDQFDDLDN 540
  541 VTIFAPTDKA LQNTEWARML KEQPELLNHN LDLLEFLNYH VVKPMIKTCD LSEKSLPTVA 600
  601 GSSVRLNLYS THALFSDVMN RATVNCARLV HFDDESCGSV LHQVDRALAP PKNNMLKLLE 660
  661 ANPNYSKFLE LVRKANLTQL LSNDSRSLTL LVPKNDIFEE LNESGEGSKP ADPMALVKTH 720
  721 IVEDVVCCAG IIPTNWPFVR SIESISGQHL RITRDRRPKI ENAGVTKCDV VATNGILHEI 780
  781 NDIIVPRPQR QQQQRPQLIP PGAGYQPQGD FDVFF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..238] PSI-BLAST 10.69897 Hybrid domain of integrin beta; Integrin beta A domain; Integrin beta tail domain; Integrin beta EGF-like domains
    2 View Details [239..505] FFAS03 6.3 Fasciclin I
    3 View Details [506..815] PSI-BLAST 42.0 Fasciclin I


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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