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View Structure Prediction Details

Protein: mfas-PH, mfas-PN
Organism: Drosophila melanogaster
Length: 815 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mfas-PH, mfas-PN.

Description E-value Query
Range
Subject
Range
mfas-PL, mfas-PD... - The gene midline fasciclin is referred to in FlyBase by the symbol Dmel\mfas (CG3359, FBgn0260745). ...
555.0 [0..12] [815..12]

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Predicted Domain #1
Region A:
Residues: [1-238]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRLWACLLL LGSIQIQAVP FYGDGYDTEF VPLEHQQQPQ GRQETAATVP AQTPSGVEQK  60
   61 PFNVDTITTD VNSPNPAIFF QQSFPFFGNE FFNSFGGFGF GAAQEPWWKG PNVCTEKEED 120
  121 ETVASETEAE ETVDTFGQER DGVTNVVRSP LFGQFQFSVN SCAEKPNKHV CTKIVNQNGK 180
  181 KKTLTLTRQC CYGYGRPRNA DFTTPCEKID IKDVEATASD MGAKQFLESA RTAGELAD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 10.69897
Match: 1jv2B
Description: Hybrid domain of integrin beta; Integrin beta A domain; Integrin beta tail domain; Integrin beta EGF-like domains
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [239-505]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLGAGSGKKV TLFVPNDAAF MEYRGHHQQE NNVEDAKAEA SKPSIYKLHA VLGEVQLEDV  60
   61 PNEKLLQTEL PDQKIRINSY QLPAALGLEP YRFAANCVPI EKHDKLSEQA LVHTLGGVLK 120
  121 PLTKNLMDII RERADMSIMR TVLEKTNLSA MLEDDKPVTI FVPTDAAFDK LEPHLRRALK 180
  181 EGRGCASNIL KNHLLDLTFC SLATVPGAKT TAYNLLGEPL LLNRTHRAAN QTGPTPIYIN 240
  241 NLAKIIDADI MGTNGVLHVI DTILPTE

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 6.3
Match: 1o70A
Description: Fasciclin I
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [506-815]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SALPMTSLMS QKNLTIFQRL LEASGYDDQF DDLDNVTIFA PTDKALQNTE WARMLKEQPE  60
   61 LLNHNLDLLE FLNYHVVKPM IKTCDLSEKS LPTVAGSSVR LNLYSTHALF SDVMNRATVN 120
  121 CARLVHFDDE SCGSVLHQVD RALAPPKNNM LKLLEANPNY SKFLELVRKA NLTQLLSNDS 180
  181 RSLTLLVPKN DIFEELNESG EGSKPADPMA LVKTHIVEDV VCCAGIIPTN WPFVRSIESI 240
  241 SGQHLRITRD RRPKIENAGV TKCDVVATNG ILHEINDIIV PRPQRQQQQR PQLIPPGAGY 300
  301 QPQGDFDVFF 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 42.0
Match: 1o70A
Description: Fasciclin I
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle