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Protein Overview: mfas-PE, mfas-PO

General Information:
Name(s) found: mfas-PO / FBpp0081976 [FlyBase]
mfas-PE / FBpp0081967 [FlyBase]
Description(s) found:
Found 32 descriptions.
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  • The gene midline fasciclin is referred to in FlyBase by the symbol Dmel\mfas (CG3359, FBgn0260745). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:7810584..7819037. It has the cytological map location 87A7-87A4. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: axonogenesis. 8 alleles are reported. No phenotypic data is available. It has 15 annotated transcripts and 15 annotated polypeptides. [FlyBase]
  • The gene midline fasciclin is referred to in FlyBase by the symbol Dmel\mfas (CG3359, FBgn0260745). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:7810584..7819037. It has the cytological map location 87A7-87A4. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: axonogenesis. 8 alleles are reported. No phenotypic data is available. It has 15 annotated transcripts and 15 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 839 amino acids

    Gene Ontology:
    Cellular Component: plasma membrane [NAS]
    Biological Process: axonogenesis [IMP]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRLWACLLL LGSIQIQAVP FYGDSSSEEV AEFDDSSDST HESSDNSSGY DTEFVPLEHQ  60
   61 QQPQGRQETA ATVPAQTPSG VEQKPFNVDT ITTDVNSPNP AIFFQQSFPF FGNEFFNSFG 120
  121 GFGFGAAQEP WWKGPNVCTE KEEDETVASE TEAEETVDTF GQERDGVTNV VRSPLFGQFQ 180
  181 FSVNSCAEKP NKHVCTKIVN QNGKKKTLTL TRQCCYGYGR PRNADFTTPC EKIDIKDVEA 240
  241 TASDMGAKQF LESARTAGEL ADMLGAGSGK KVTLFVPNDA AFMEYRGHHQ QENNVEDAKA 300
  301 EASKPSIYKL HAVLGEVQLE DVPNEKLLQT ELPDQKIRIN SYQLPAALGL EPYRFAANCV 360
  361 PIEKHDKLSE QALVHTLGGV LKPLTKNLMD IIRERADMSI MRTVLEKTNL SAMLEDDKPV 420
  421 TIFVPTDAAF DKLEPHLRRA LKEGRGCASN ILKNHLLDLT FCSLATVPGA KTTAYNLLGE 480
  481 PLLLNRTHRA ANQTGPTPIY INNLAKIIDA DIMGTNGVLH VIDTILPTES ALPMTSLMSQ 540
  541 KNLTIFQRLL EASGYDDQFD DLDNVTIFAP TDKALQNTEW ARMLKEQPEL LNHNLDLLEF 600
  601 LNYHVVKPMI KTCDLSEKSL PTVAGSSVRL NLYSTHALFS DVMNRATVNC ARLVHFDDES 660
  661 CGSVLHQVDR ALAPPKNNML KLLEANPNYS KFLELVRKAN LTQLLSNDSR SLTLLVPKND 720
  721 IFEELNESGE GSKPADPMAL VKTHIVEDVV CCAGIIPTNW PFVRSIESIS GQHLRITRDR 780
  781 RPKIENAGVT KCDVVATNGI LHEINDIIVP RPQRQQQQRP QLIPPGAGYQ PQGDFDVFF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..245] PSI-BLAST 18.69897 Hybrid domain of integrin beta; Integrin beta A domain; Integrin beta tail domain; Integrin beta EGF-like domains
    2 View Details [246..539] FFAS03 6.78 Fasciclin I
    3 View Details [540..839] PSI-BLAST 43.69897 Fasciclin I


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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