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View Structure Prediction Details

Protein: mfas-PE, mfas-PO
Organism: Drosophila melanogaster
Length: 839 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mfas-PE, mfas-PO.

Description E-value Query
Range
Subject
Range
mfas-PF, mfas-PG... - The gene midline fasciclin is referred to in FlyBase by the symbol Dmel\mfas (CG3359, FBgn0260745). ...
531.0 [0..12] [839..12]

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Predicted Domain #1
Region A:
Residues: [1-245]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRLWACLLL LGSIQIQAVP FYGDSSSEEV AEFDDSSDST HESSDNSSGY DTEFVPLEHQ  60
   61 QQPQGRQETA ATVPAQTPSG VEQKPFNVDT ITTDVNSPNP AIFFQQSFPF FGNEFFNSFG 120
  121 GFGFGAAQEP WWKGPNVCTE KEEDETVASE TEAEETVDTF GQERDGVTNV VRSPLFGQFQ 180
  181 FSVNSCAEKP NKHVCTKIVN QNGKKKTLTL TRQCCYGYGR PRNADFTTPC EKIDIKDVEA 240
  241 TASDM

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 18.69897
Match: 1jv2B
Description: Hybrid domain of integrin beta; Integrin beta A domain; Integrin beta tail domain; Integrin beta EGF-like domains
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [246-539]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GAKQFLESAR TAGELADMLG AGSGKKVTLF VPNDAAFMEY RGHHQQENNV EDAKAEASKP  60
   61 SIYKLHAVLG EVQLEDVPNE KLLQTELPDQ KIRINSYQLP AALGLEPYRF AANCVPIEKH 120
  121 DKLSEQALVH TLGGVLKPLT KNLMDIIRER ADMSIMRTVL EKTNLSAMLE DDKPVTIFVP 180
  181 TDAAFDKLEP HLRRALKEGR GCASNILKNH LLDLTFCSLA TVPGAKTTAY NLLGEPLLLN 240
  241 RTHRAANQTG PTPIYINNLA KIIDADIMGT NGVLHVIDTI LPTESALPMT SLMS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 6.78
Match: 1o70A
Description: Fasciclin I
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [540-839]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QKNLTIFQRL LEASGYDDQF DDLDNVTIFA PTDKALQNTE WARMLKEQPE LLNHNLDLLE  60
   61 FLNYHVVKPM IKTCDLSEKS LPTVAGSSVR LNLYSTHALF SDVMNRATVN CARLVHFDDE 120
  121 SCGSVLHQVD RALAPPKNNM LKLLEANPNY SKFLELVRKA NLTQLLSNDS RSLTLLVPKN 180
  181 DIFEELNESG EGSKPADPMA LVKTHIVEDV VCCAGIIPTN WPFVRSIESI SGQHLRITRD 240
  241 RRPKIENAGV TKCDVVATNG ILHEINDIIV PRPQRQQQQR PQLIPPGAGY QPQGDFDVFF 300
  301 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 43.69897
Match: 1o70A
Description: Fasciclin I
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
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