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Protein Overview: nmdyn-D7-PA

General Information:
Name(s) found: nmdyn-D7-PA / FBpp0081561 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene nmdyn-D7 is referred to in FlyBase by the symbol Dmel\nmdyn-D7 (CG8362, FBgn0028997). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:5505663..5507224. It has the cytological map location 85E4. Based on sequence similarity, it is predicted to have molecular function</span>: nucleoside diphosphate kinase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: GTP biosynthetic process; CTP biosynthetic process; UTP biosynthetic process. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 387 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: UTP biosynthetic process [IEA]
    CTP biosynthetic process [IEA]
    GTP biosynthetic process [IEA]
    Molecular Function: ATP binding [IEA]
    nucleoside diphosphate kinase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKPAAIPASE RRLAFVAEWF HAEAGIIRTF LITYYVSDKA VEVFDQRNKR TFLRRTKIPE  60
   61 LTQRDFFVGS KINVFGRQFD IVDYADDTTR TNLAKYRKKG FVLLKNNMWT KHLGKFLKTL 120
  121 IDNKININQG MMVQFSPKMV TQFLSGKDTT DVSSSVLMNE LLAGPAISLE LIGDNVVETI 180
  181 KACAQYKSTE AETPSVKLSP SLEELFESEE IRYGFYYSDN DNDVEMDLKF ISEARHSIIK 240
  241 ECVFKNTTLA IIKPHSIKDG LLGDIISEIL SNGFRLTAMR MILMARINCE EFYEVYRGVV 300
  301 PEYIPMVAQL ASGVCMCMEI ACADPEKKTD REFRNFCGPM DPEIAKLLRP HTLRAKFGKS 360
  361 KVQNAVHCTD LPDDSNLELQ YMFKIID

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..96] deduced N/A No confident structure predictions are available.
    2 View Details [97..245] FFAS03 6.61 Crystal Structure of Nucleoside Diphosphate Kinase from Thermus thermophilus HB8
    3 View Details [246..387] PSI-BLAST 56.522879 Nucleoside diphosphate kinases

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • nucleobase, nucleoside, nucleotide kinase activity
    		•  6.4448415473479 bayes_pls_golite062009
  • phosphotransferase activity, phosphate group as acceptor
    		•  5.85502930858634 bayes_pls_golite062009
  • nucleoside diphosphate kinase activity
    		•  4.61067707314941 bayes_pls_golite062009
  • kinase activity
    		•  4.26784564496601 bayes_pls_golite062009
  • catalytic activity
    		•  1.80062327922062 bayes_pls_golite062009
  • transferase activity
    		•  0.96744394416511 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.752351123941402 bayes_pls_golite062009
    3
    Term Confidence Notes
  • nucleobase, nucleoside, nucleotide kinase activity
    		•  7.03061421339491 bayes_pls_golite062009
  • phosphotransferase activity, phosphate group as acceptor
    		•  6.44414487354776 bayes_pls_golite062009
  • nucleoside diphosphate kinase activity
    		•  5.37425936177415 bayes_pls_golite062009
  • kinase activity
    		•  4.60914087199794 bayes_pls_golite062009
  • catalytic activity
    		•  1.91319552351397 bayes_pls_golite062009
  • transferase activity
    		•  1.21163341858368 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.06719669551075 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.83

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle