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View Structure Prediction Details

Protein: nmdyn-D7-PA
Organism: Drosophila melanogaster
Length: 387 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for nmdyn-D7-PA.

Description E-value Query
Range
Subject
Range
NDK7_RAT - Nucleoside diphosphate kinase 7 OS=Rattus norvegicus GN=Nme7 PE=1 SV=1
418.0 [0..1] [387..13]

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Predicted Domain #1
Region A:
Residues: [1-96]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKPAAIPASE RRLAFVAEWF HAEAGIIRTF LITYYVSDKA VEVFDQRNKR TFLRRTKIPE  60
   61 LTQRDFFVGS KINVFGRQFD IVDYADDTTR TNLAKY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [97-245]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RKKGFVLLKN NMWTKHLGKF LKTLIDNKIN INQGMMVQFS PKMVTQFLSG KDTTDVSSSV  60
   61 LMNELLAGPA ISLELIGDNV VETIKACAQY KSTEAETPSV KLSPSLEELF ESEEIRYGFY 120
  121 YSDNDNDVEM DLKFISEARH SIIKECVFK

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 6.61
Match: 1wkjA
Description: Crystal Structure of Nucleoside Diphosphate Kinase from Thermus thermophilus HB8
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleobase, nucleoside, nucleotide kinase activity 6.4448415473479 bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor 5.85502930858634 bayes_pls_golite062009
nucleoside diphosphate kinase activity 4.61067707314941 bayes_pls_golite062009
kinase activity 4.26784564496601 bayes_pls_golite062009
catalytic activity 1.80062327922062 bayes_pls_golite062009
transferase activity 0.96744394416511 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.752351123941402 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [246-387]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTTLAIIKPH SIKDGLLGDI ISEILSNGFR LTAMRMILMA RINCEEFYEV YRGVVPEYIP  60
   61 MVAQLASGVC MCMEIACADP EKKTDREFRN FCGPMDPEIA KLLRPHTLRA KFGKSKVQNA 120
  121 VHCTDLPDDS NLELQYMFKI ID

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 56.522879
Match: 1jxvA
Description: Nucleoside diphosphate kinases
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
nucleobase, nucleoside, nucleotide kinase activity 7.03061421339491 bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor 6.44414487354776 bayes_pls_golite062009
nucleoside diphosphate kinase activity 5.37425936177415 bayes_pls_golite062009
kinase activity 4.60914087199794 bayes_pls_golite062009
catalytic activity 1.91319552351397 bayes_pls_golite062009
transferase activity 1.21163341858368 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.06719669551075 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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