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Protein Overview: CG8129-PA

General Information:
Name(s) found: CG8129-PA / FBpp0081505 [FlyBase]
Description(s) found:
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  • gi|7299167|gb|AAF54365.1| CG8129, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|24645328|ref|NP_731340.1| CG8129, isoform A [Drosophila melanogaster] [NCBI NR]
  • This gene is referred to in FlyBase by the symbol Dmel\CG8129 (CG8129, FBgn0037684). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:5191142..5193488. It has the cytological map location 85D12-85D13. Based on sequence similarity, it is predicted to have molecular function</span>: L-threonine ammonia-lyase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: metabolic process. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • >CG8129-PA translation from_gene[CG8129 CG8129 FBgn0037684] seq_release:3 mol_weight=34030 cds_boundaries:(3R:5,192,265..5,193,333[+]) aa_length:316 transcript_info:[CG8129-RA seq_release:3] gene_info:[gene symbol:CG8129 FBgn0037684 gene_boundaries:(3R [hmr_yeast5_DM3-1_pombe.fasta]
  • (AE003682) CG8129 gene product [alt 2] [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG8129-PA, isoform A [Drosophila melanogaster]gi|24645328|ref|NP_731340.1| CG8129-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:join(5192249..5192554,5192612..5192904,5192969..5193320); ID=FBpp0081505; name=CG8129-PA; parent=FBgn0037684,FBtr0082027; dbxref=FlyBase:FBpp0081505,FlyBase_Annotation_IDs:CG8129-PA,GB_protein:AAF54365.1,REFSEQ:NP_731340,GB_protein:AA [fly-100309-contam.fasta]
  • CG8129-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:join(5192249..5192554,5192612..5192904,5192969..5193320); ID=FBpp0081505; name=CG8129-PA; parent=FBgn0037684,FBtr0082027; dbxref=FlyBase:FBpp0081505,FlyBase_Annotation_IDs:CG8129-PA,GB_protein:AAF54365.1,REFSEQ:NP_731340,GB_protein:AAF54365; MD5=a8a8342edb3c84dab7c57adaf752fec4; length=316; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:join(5192249..5192554,5192612..5192904,5192969..5193320); ID=FBpp0081505; name=CG8129-PA; parent=FBgn0037684,FBtr0082027; dbxref=FlyBase:FBpp0081505,FlyBase_Annotation_IDs:CG8129-PA,GB_protein:AAF54365.1,REFSEQ:NP_731340,GB_protein:AAF54365; MD5=a8a8342edb3c84dab7c57adaf752fec4; length=316; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • CG8129, isoform A OS=Drosophila melanogaster GN=CG8129 PE=4 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3R:join(5192249..5192554,5192612..5192904,5192969..5193320); ID=FBpp0081505; name=CG8129-PA; parent=FBgn0037684,FBtr0082027; dbxref=FlyBase:FBpp0081505,FlyBase_Annotation_IDs:CG8129-PA,GB_protein:AAF54365.1,REFSEQ:NP_731340,GB_protein:AAF54365,FlyMine:FBpp0081505,modMine:FBpp0081505; MD5=a8a8342edb3c84dab7c57adaf752fec4; length=316; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:join(9366527..9366832,9366890..9367182,9367247..9367598); ID=FBpp0081505; name=CG8129-PA; parent=FBgn0037684,FBtr0082027; dbxref=FlyBase:FBpp0081505,FlyBase_Annotation_IDs:CG8129-PA,GB_protein:AAF54365.1,REFSEQ:NP_731340,GB_protein:AAF54365,FlyMine:FBpp0081505,modMine:FBpp0081505; MD5=a8a8342edb3c84dab7c57adaf752fec4; length=316; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:join(9366527..9366832,9366890..9367182,9367247..9367598); ID=FBpp0081505; name=CG8129-PA; parent=FBgn0037684,FBtr0082027; dbxref=FlyBase:FBpp0081505,FlyBase_Annotation_IDs:CG8129-PA,GB_protein:AAF54365.1,REFSEQ:NP_731340,GB_protein:AAF54365,FlyMine:FBpp0081505,modMine:FBpp0081505; MD5=a8a8342edb3c84dab7c57adaf752fec4; length=316; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of Q9VHF0, CG8129, isoform A OS=Drosophila melanogaster GN=CG8129 PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0081505 type=protein; loc=3R:join(9366527..9366832,9366890..9367182,9367247..9367598); ID=FBpp0081505; name=CG8129-PA; parent=FBgn0037684,FBtr0082027; dbxref=FlyBase:FBpp0081505,FlyBase_Annotation_IDs:CG8129-PA,GB_protein:AAF54365.1,REFSEQ:NP_731340,GB_protein:AAF54365,FlyMine:FBpp0081505,modMine:FBpp0081505; MD5=a8a8342edb3c84dab7c57adaf752fec4; length=316; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3R:join(9366527..9366832,9366890..9367182,9367247..9367598); ID=FBpp0081505; name=CG8129-PA; parent=FBgn0037684,FBtr0082027; dbxref=FlyBase:FBpp0081505,FlyBase_Annotation_IDs:CG8129-PA,GB_protein:AAF54365.1,REFSEQ:NP_731340,GB_protein:AAF54365,UniProt/TrEMBL:Q7KST5,FlyMine:FBpp0081505,modMine:FBpp0081505; MD5=a8a8342edb3c84dab7c57adaf752fec4; length=316; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 316 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: metabolic process [IEA]
    Molecular Function: pyridoxal phosphate binding [IEA]
    amino acid binding [IEA]
    L-threonine ammonia-lyase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPKAAPIMKI QKCRNYKARV IVDGNDMGEA KSLAMRMSRE EGLLYVNGYD HPHIMAGQGT  60
   61 IGLEILEQVP EPDAVVVPVG GGGLIAGIAT AVKALSPKTK IIGVESEKCA SFTRAMENDG 120
  121 PIHTPIKNTL ADGLAVPKVG YNAYATAMPL IDRMVVVKEE WIAVAILRLV EEEKCVVEGA 180
  181 GGAGLAAILA GHLDELKGKK VVVLLCGGNI DTTVFGRCLE RGLAAVGRLV KFNVEVSDRP 240
  241 GGINDLCALL VRVGVSIKDI MHERAWLRDV YTVEVKVVCE TVDWTHSLQL KNELKKFYSK 300
  301 VQFSDVPLAL SNDTDS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..316] PSI-BLAST 74.30103 THREONINE DEAMINASE (BIOSYNTHETIC) FROM E. COLI

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • lyase activity
    		•  0.92121242786289 bayes_pls_golite062009
  • catalytic activity
    		•  0.115197515122073 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle