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Protein Overview: CG8129-PB

General Information:
Name(s) found: CG8129-PB / FBpp0081504 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG8129 (CG8129, FBgn0037684). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:5191142..5193488. It has the cytological map location 85D12-85D13. Based on sequence similarity, it is predicted to have molecular function</span>: L-threonine ammonia-lyase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: metabolic process. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 469 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: metabolic process [IEA]
    Molecular Function: pyridoxal phosphate binding [IEA]
    amino acid binding [IEA]
    L-threonine ammonia-lyase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQAVKTETP KEPNVVAAKA NGGTAVNGKL EAQKRPRHVS GGVEEIIDPF CNPEKPQRIS  60
   61 FHDVTSAAFL IRGGVERTPC PKSTSSDLYG MELYLKKDFL QYTGSFKERG ARYALLSLTE 120
  121 EQKRTGVISA SLGNHAQALC YHGWKLNIPV TVVMPKAAPI MKIQKCRNYK ARVIVDGNDM 180
  181 GEAKSLAMRM SREEGLLYVN GYDHPHIMAG QGTIGLEILE QVPEPDAVVV PVGGGGLIAG 240
  241 IATAVKALSP KTKIIGVESE KCASFTRAME NDGPIHTPIK NTLADGLAVP KVGYNAYATA 300
  301 MPLIDRMVVV KEEWIAVAIL RLVEEEKCVV EGAGGAGLAA ILAGHLDELK GKKVVVLLCG 360
  361 GNIDTTVFGR CLERGLAAVG RLVKFNVEVS DRPGGINDLC ALLVRVGVSI KDIMHERAWL 420
  421 RDVYTVEVKV VCETVDWTHS LQLKNELKKF YSKVQFSDVP LALSNDTDS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..59] PSI-BLAST 70.69897 Cystathionine beta-synthase
    2 View Details [60..469] PSI-BLAST 102.0 THREONINE DEAMINASE (BIOSYNTHETIC) FROM E. COLI

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • acetolactate synthase activity
    		•  6.25735158730374 bayes_pls_golite062009
  • transferase activity, transferring aldehyde or ketonic groups
    		•  5.28856942236052 bayes_pls_golite062009
  • threonine racemase activity
    		•  4.44340924206787 bayes_pls_golite062009
  • threonine synthase activity
    		•  3.59927532963055 bayes_pls_golite062009
  • cysteine synthase activity
    		•  3.57860549303214 bayes_pls_golite062009
  • L-threonine ammonia-lyase activity
    		•  3.33109959091277 bayes_pls_golite062009
  • tryptophan synthase activity
    		•  1.99526226543975 bayes_pls_golite062009
  • lyase activity
    		•  1.87743897464083 bayes_pls_golite062009
  • carbon-oxygen lyase activity
    		•  0.923824749425553 bayes_pls_golite062009
  • binding
    		•  0.887909702374337 bayes_pls_golite062009
  • catalytic activity
    		•  0.645256181736122 bayes_pls_golite062009
  • ammonia-lyase activity
    		•  0.476674617721478 bayes_pls_golite062009
  • carbon-nitrogen lyase activity
    		•  0.249761226675912 bayes_pls_golite062009
  • protein binding
    		•  0.219210115869644 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle