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View Structure Prediction Details

Protein: CG8129-PB
Organism: Drosophila melanogaster
Length: 469 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG8129-PB.

Description E-value Query
Range
Subject
Range
gi|90415223|ref|... - threonine dehydratase [marine gamma proteobacterium HTCC2207]
gi|90415223, gi|... - gi|90415223|ref|ZP_01223157.1| threonine dehydratase [marine gamma proteobacterium HTCC2207], gi|903...
409.0 [0..67] [465..10]

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Predicted Domain #1
Region A:
Residues: [1-59]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSQAVKTETP KEPNVVAAKA NGGTAVNGKL EAQKRPRHVS GGVEEIIDPF CNPEKPQRI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 70.69897
Match: 1jbqA
Description: Cystathionine beta-synthase
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [60-469]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SFHDVTSAAF LIRGGVERTP CPKSTSSDLY GMELYLKKDF LQYTGSFKER GARYALLSLT  60
   61 EEQKRTGVIS ASLGNHAQAL CYHGWKLNIP VTVVMPKAAP IMKIQKCRNY KARVIVDGND 120
  121 MGEAKSLAMR MSREEGLLYV NGYDHPHIMA GQGTIGLEIL EQVPEPDAVV VPVGGGGLIA 180
  181 GIATAVKALS PKTKIIGVES EKCASFTRAM ENDGPIHTPI KNTLADGLAV PKVGYNAYAT 240
  241 AMPLIDRMVV VKEEWIAVAI LRLVEEEKCV VEGAGGAGLA AILAGHLDEL KGKKVVVLLC 300
  301 GGNIDTTVFG RCLERGLAAV GRLVKFNVEV SDRPGGINDL CALLVRVGVS IKDIMHERAW 360
  361 LRDVYTVEVK VVCETVDWTH SLQLKNELKK FYSKVQFSDV PLALSNDTDS 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 102.0
Match: 1tdjA
Description: THREONINE DEAMINASE (BIOSYNTHETIC) FROM E. COLI
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
acetolactate synthase activity 6.25735158730374 bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups 5.28856942236052 bayes_pls_golite062009
threonine racemase activity 4.44340924206787 bayes_pls_golite062009
threonine synthase activity 3.59927532963055 bayes_pls_golite062009
cysteine synthase activity 3.57860549303214 bayes_pls_golite062009
L-threonine ammonia-lyase activity 3.33109959091277 bayes_pls_golite062009
tryptophan synthase activity 1.99526226543975 bayes_pls_golite062009
lyase activity 1.87743897464083 bayes_pls_golite062009
carbon-oxygen lyase activity 0.923824749425553 bayes_pls_golite062009
binding 0.887909702374337 bayes_pls_golite062009
catalytic activity 0.645256181736122 bayes_pls_golite062009
ammonia-lyase activity 0.476674617721478 bayes_pls_golite062009
carbon-nitrogen lyase activity 0.249761226675912 bayes_pls_golite062009
protein binding 0.219210115869644 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle