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Protein Overview: CG8007-PB

General Information:
Name(s) found: CG8007-PB / FBpp0081366 [FlyBase]
Description(s) found:
Found 11 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG8007 (CG8007, FBgn0037600). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:4445477..4452743. It has the cytological map location 85A5. Based on sequence similarity, it is predicted to have molecular function</span>: G-protein coupled serotonin receptor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: serotonin receptor signaling pathway. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 778 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [ISS]
    Biological Process: serotonin receptor signaling pathway [ISS]
    Molecular Function: G-protein coupled serotonin receptor activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKNRFFFSFT GYFPLGSEHC LTWICLDVLF CTASIMHLCT ISVDRYLSLR YPMRFGRNKT  60
   61 RRRVTLKIVF VWLLSIAMSL PLSLMYSKNH ASVLVNGTCQ IPDPVYKLVG SIVCFYIPLG 120
  121 VMLLTYCLTV RLLARQRQNL GGGQQTAAAT PGWASGWLGQ APALERRCTW RRLLKPGPGN 180
  181 ASSVLHAHSA NSTDTDLSTL DNHELWLPDS SIKEPTPTTM TALHQFGAEM LKLSRGLESV 240
  241 ASSSTTGSPT KSEFSLSNHL QLQYPSSPQR YAATHQQSHH HNHQQHPAGV YHQQASPKGR 300
  301 HGTTVLGLST TTLGIEREST RNSLASSRMG GEQSDGTLSQ LSQRLRAYKK RRRASSAVPG 360
  361 REKRAGHEDA DEDVETPTST LRRHKRHNSL PKNALYPRHT TVQESLDDDD DEEEESAQQK 420
  421 DQQTKSKICH SDTELDPPQK AKQCHIAGQN HQSDYLQLPS VCTCPYFGDR PLQNCVKSAE 480
  481 VKIISSAFRV TTTTTAVSSS PSEMELLMCS SGNKKSLTSS VSAGITGGPA GAAPATVGST 540
  541 LSPHSAHNQG SSLTVQSDGS GYLAAPGTPC PGRRKLSISK TASVVTWDSS RHRRRGSSFG 600
  601 GVRTSLLLTP TKTATTSNSS TPLRRSATLR SHQNMNYQGA GECGGKTRTT TSSPCMLQRQ 660
  661 QTVRSHHSRN SSVISRNSSR HGRIIRLEQK ATKVLGVVFF TFVILWSPFF VLNLLPTVCA 720
  721 ECEERISHWV FDVVTWLGYA SSMVNPIFYT IFNKVFRQAF KKVLLCRYSS TSAWRPSR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..248] PSI-BLAST 30.0 Rhodopsin
    2 View Details [249..778] FFAS03 2.2 Rhodopsin


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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