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Protein Overview: FBpp0308676, DNA...

General Information:
Name(s) found: FBpp0308676 [FlyBase]
DNApol-iota-PA / FBpp0081294 [FlyBase]
DNApol-iota-PB / FBpp0081293 [FlyBase]
Description(s) found:
Found 42 descriptions.
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  • type=protein; loc=3R:join(4059988..4060944,4061009..4062265); ID=FBpp0308676; name=DNApol-iota-PC; parent=FBgn0037554,FBtr0339606; dbxref=FlyBase:FBpp0308676,FlyBase_Annotation_IDs:CG7602-PC; MD5=71e6c138f4b34a2c0e936cfd2c64813f; length=737; release=r5.56; species=Dmel; [FlyBase]
  • The gene DNApol-Ã?&#142;Ã?¹ is referred to in FlyBase by the symbol Dmel\DNApol-Ã?&#142;Ã?¹ (CG7602, FBgn0037554). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:4059229..4062528. It has the cytological map location 84F4-84F5. There is experimental evidence that it has the molecular function</span>: DNA-directed DNA polymerase activity. There is experimental evidence that it is involved in the biological process</span>: translesion synthesis. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • The gene DNApol-Ã?&#142;Ã?¹ is referred to in FlyBase by the symbol Dmel\DNApol-Ã?&#142;Ã?¹ (CG7602, FBgn0037554). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:4059229..4062528. It has the cytological map location 84F4-84F5. There is experimental evidence that it has the molecular function</span>: DNA-directed DNA polymerase activity. There is experimental evidence that it is involved in the biological process</span>: translesion synthesis. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 737 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: translesion synthesis [IDA][ISS][NAS]
    Molecular Function: DNA-directed DNA polymerase activity [IDA][IMP][NAS]
    damaged DNA binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDFASVLGKS EAHQRTIIHL DMDYFYAQVE EIRDPTLRSK ALGIQQKNIV VTCNYVARAK  60
   61 GVTKLMLIAE AQRICPDLVL VNGEDLAPYR QMSQRIFDLL LNYTPLVEKL GFDENFMDVT 120
  121 ALVELRQAHV AEALLRPPVG HTYPADGTPL SNCDCGCAQR LAIGTRIAQE IREELKLRLG 180
  181 ITCCAGIAYN KLLAKLVGSS HEPNQQTVLV STYAEQFMRE LGDLKRVTGI GQKTQCLLLE 240
  241 AGMSSVEQLQ QCDMDVMRKK FGFETATRLR DLAFGRDTSL VRPSGKPKTI GMEDACKPIS 300
  301 VRTDVEERFR MLLKRLVEQV AEDGRVPIAI KVVLRKFDSQ KKSSHRETKQ ANILPSLFKT 360
  361 SMCPGETGVS KVQLADGAQD KLLKIVMRLF ERIVDMSKPF NITLLGLAFS KFQERKVGSS 420
  421 SIANFLIKKA DLEVQSITSL TNTSLTSPTA ESPTSDECAF RSSPTTFKPS DQFYRRRATT 480
  481 ASPVPMLLDN GSESAATNSD FSDFSETEVE PSPKKSRIGR LLVSKRSRLA ADVGDSAAEV 540
  541 ASPSKLRVCD LRLNSRDSEK DFPMSTTPST STSAPAPRFR TVQPPNTLLQ RIDGSLRFVT 600
  601 TRTASRLSSN ASSTASSPLP SPMDDSIAMS APSTTTLPFP SPTTTAVVTS SSSTATCDAL 660
  661 TNIVCPAGVD AEVFKELPVE LQTELIASWR SSLVAAVEQT NGTGAATSAA IASGAPATAT 720
  721 TASGQKNTLY RYFLRNK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..434] PSI-BLAST 97.0 No description for 2dpiA was found.
    2 View Details [435..662] MSA 2.248996 View MSA. No confident structure predictions are available.
    3 View Details [663..737] MSA 2.219995 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • DNA-directed DNA polymerase activity
    		•  4.38129837827821 bayes_pls_golite062009
  • DNA polymerase activity
    		•  4.37339889806547 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  3.39575274291906 bayes_pls_golite062009
  • catalytic activity
    		•  1.41943047378765 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.03192827597738 bayes_pls_golite062009
  • transferase activity
    		•  0.98512909175458 bayes_pls_golite062009
  • DNA primase activity
    		•  0.6264375547938 bayes_pls_golite062009
  • exonuclease activity
    		•  0.20278066435985 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.00586413250727191 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle