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Protein Overview: puc-PA

General Information:
Name(s) found: puc-PA / FBpp0081288 [FlyBase]
Description(s) found:
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  • gi|7298988|gb|AAF54191.1| puckered [Drosophila melanogaster] [NCBI NR]
  • gi|17737839|ref|NP_524273.1| puckered [Drosophila melanogaster] [NCBI NR]
  • gi|16769890|gb|AAL29164.1| SD08157p [Drosophila melanogaster] [NCBI NR]
  • The gene puckered is referred to in FlyBase by the symbol Dmel\puc (CG7850, FBgn0243512). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:3931057..3948023. It has the cytological map location 84E12-84E11. There is experimental evidence that it has the molecular function</span>: JUN kinase phosphatase activity; phosphoprotein phosphatase activity. There is experimental evidence for 20 unique biological process</span> terms, many of which group under: anatomical structure development; reproductive process in a multicellular organism; organ development; organ morphogenesis; regulation of biological process; actin filament-based process; ovarian follicle cell development; regulation of developmental process; response to stress; organelle organization. 54 alleles are reported. The phenotypes of these alleles are annotated with 26 unique terms, many of which group under: organ system; egg; cuticle; peripheral nervous system; external compound sense organ; adult segment; nervous system; chorion; adult mesothoracic segment; cuticular specialization. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG7850-PA translation from_gene[CG7850 puc FBgn0004210] seq_release:3 mol_weight=51271 cds_boundaries:(3R:3,931,598..3,947,069[+]) aa_length:476 transcript_info:[CG7850-RA seq_release:3] gene_info:[gene symbol:puc FBgn0004210 gene_boundaries:(3R:3,931 [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9VHV8) PUC protein (SD08157P) [DrosMelano7227.FASTAC.txt]
  • (AE003677) puc gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG7850-PA [Drosophila melanogaster]gi|16769890|gb|AAL29164.1| SD08157p [Drosophila melanogaster]gi|17737839|ref|NP_524273.1| CG7850-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=3R:join(3931583..3931817,3933954..3934100,3936799..3937023,3946234..3947057); ID=FBpp0081288; name=puc-PA; parent=FBgn0243512,FBtr0081792; dbxref=FlyBase:FBpp0081288,FlyBase_Annotation_IDs:CG7850-PA,GB_protein:AAF54191.1,REFSEQ:NP_524273 [fly-100309-contam.fasta]
  • puckered CG7850-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • SD08157p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG7850-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=3R:join(3931583..3931817,3933954..3934100,3936799..3937023,3946234..3947057); ID=FBpp0081288; name=puc-PA; parent=FBgn0243512,FBtr0081792; dbxref=FlyBase:FBpp0081288,FlyBase_Annotation_IDs:CG7850-PA,GB_protein:AAF54191.1,REFSEQ:NP_524273,GB_protein:AAF54191; MD5=0951078f61cd172bcbd38ae7f13d0bb2; length=476; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=3R:join(3931583..3931817,3933954..3934100,3936799..3937023,3946234..3947057); ID=FBpp0081288; name=puc-PA; parent=FBgn0243512,FBtr0081792; dbxref=FlyBase:FBpp0081288,FlyBase_Annotation_IDs:CG7850-PA,GB_protein:AAF54191.1,REFSEQ:NP_524273,GB_protein:AAF54191; MD5=0951078f61cd172bcbd38ae7f13d0bb2; length=476; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Puckered OS=Drosophila melanogaster GN=puc PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=3R:join(3931583..3931817,3933954..3934100,3936799..3937023,3946234..3947057); ID=FBpp0081288; name=puc-PA; parent=FBgn0243512,FBtr0081792; dbxref=FlyBase:FBpp0081288,FlyBase_Annotation_IDs:CG7850-PA,GB_protein:AAF54191.1,REFSEQ:NP_524273,GB_protein:AAF54191,FlyMine:FBpp0081288,modMine:FBpp0081288; MD5=0951078f61cd172bcbd38ae7f13d0bb2; length=476; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=3R:join(8105861..8106095,8108232..8108378,8111077..8111301,8120512..8121335); ID=FBpp0081288; name=puc-PA; parent=FBgn0243512,FBtr0081792; dbxref=FlyBase:FBpp0081288,FlyBase_Annotation_IDs:CG7850-PA,GB_protein:AAF54191.1,REFSEQ:NP_524273,GB_protein:AAF54191,FlyMine:FBpp0081288,modMine:FBpp0081288; MD5=0951078f61cd172bcbd38ae7f13d0bb2; length=476; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=3R:join(8105861..8106095,8108232..8108378,8111077..8111301,8120512..8121335); ID=FBpp0081288; name=puc-PA; parent=FBgn0243512,FBtr0081792; dbxref=FlyBase:FBpp0081288,FlyBase_Annotation_IDs:CG7850-PA,GB_protein:AAF54191.1,REFSEQ:NP_524273,GB_protein:AAF54191,FlyMine:FBpp0081288,modMine:FBpp0081288; MD5=0951078f61cd172bcbd38ae7f13d0bb2; length=476; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Puckered, isoform A OS=Drosophila melanogaster GN=puc PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0081288 type=protein; loc=3R:join(8105861..8106095,8108232..8108378,8111077..8111301,8120512..8121335); ID=FBpp0081288; name=puc-PA; parent=FBgn0243512,FBtr0081792; dbxref=FlyBase:FBpp0081288,FlyBase_Annotation_IDs:CG7850-PA,GB_protein:AAF54191.1,REFSEQ:NP_524273,GB_protein:AAF54191,FlyMine:FBpp0081288,modMine:FBpp0081288; MD5=0951078f61cd172bcbd38ae7f13d0bb2; length=476; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=3R:join(8105861..8106095,8108232..8108378,8111077..8111301,8120512..8121335); ID=FBpp0081288; name=puc-PA; parent=FBgn0243512,FBtr0081792; dbxref=FlyBase:FBpp0081288,FlyBase_Annotation_IDs:CG7850-PA,GB_protein:AAF54191.1,REFSEQ:NP_524273,GB_protein:AAF54191,UniProt/TrEMBL:Q9VHV8,FlyMine:FBpp0081288,modMine:FBpp0081288; MD5=0951078f61cd172bcbd38ae7f13d0bb2; length=476; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 476 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [IDA]
    Golgi apparatus [IDA]
    Biological Process: dorsal closure [IMP][NAS][TAS]
    regulation of cell shape [IMP]
    suture of dorsal opening [NAS]
    determination of adult lifespan [IMP]
    chitin-based embryonic cuticle biosynthetic process [IMP]
    epidermis development [IMP]
    actin filament organization [IMP]
    JNK cascade [IMP][NAS][TAS]
    border follicle cell migration [IGI]
    response to oxidative stress [IMP]
    wound healing [IDA][IEP][IMP]
    ovarian follicle cell development [IMP][TAS]
    ommatidial rotation [NAS]
    imaginal disc eversion [IMP]
    protein amino acid dephosphorylation [IDA][ISS][NAS]
    peripheral nervous system development [TAS]
    dorsal appendage formation [IMP]
    negative regulation of JNK cascade [NAS][TAS]
    imaginal disc fusion [IMP]
    compound eye development [IMP]
    micropyle formation [IMP]
    negative regulation of apoptosis [IMP]
    establishment of planar polarity [NAS]
    actin cytoskeleton organization [IMP]
    regulation of G2/M transition of mitotic cell cycle [IMP]
    Molecular Function: phosphoprotein phosphatase activity [IDA]
    protein tyrosine phosphatase activity [IEA][ISS]
    MAP kinase tyrosine/serine/threonine phosphatase activity [NAS][TAS]
    JUN kinase phosphatase activity [IMP][NAS][TAS]
    protein tyrosine/serine/threonine phosphatase activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MCVNRETQSS SNNNSNNTTT ATSTARNNNS HNGRCECDGD GDSVSHIQSE MKMRIKREAP  60
   61 CLLLFMPIQN TNNNNRIGAN QKDYPNKRSR ENLACDEVTS TTSSSTAMNG GGRTPALTRS 120
  121 CSSPAVYDIE THPASPVFPH LLLGNGRDAD DPSSVGANCV LNVTCQSPNE SHLQGLKYMQ 180
  181 IPASDTPHQN IKQYFQEAYD FIEDARKTGS RVLLHCHAGI SRSATIAIAY VMRYKSLSLL 240
  241 EAYKLVKVAR PIISPNLNFM GQLLELEQNL RKSGVLAPAT PHLNSPSNPS SSSVGLSTQS 300
  301 SQLVEQPEEE EKREQRERGK SKSDSEAMDE DGFDYDDVDS GSGSLAGSNC SSRLTSPPIT 360
  361 PDDEAPSTSA AASSVSELDS PSSTSSSSGI CSLLQSTSSS VSPRAISKPN LLSPTRQLAL 420
  421 FKRNSPAKLR LDLESSYAPA SPIPNTMPWL SVPSTPVCEE APDSRINHVA SNLTRD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..128] PSI-BLAST 14.0 No description for 2oucA was found.
    2 View Details [129..287] PSI-BLAST 34.30103 No description for 2oudA was found.
    3 View Details [288..476] MSA 16.257997 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle