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Protein Overview: Tom34-PA

General Information:
Name(s) found: Tom34-PA / FBpp0081284 [FlyBase]
Description(s) found:
Found 23 descriptions.
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  • The gene Translocase of outer membrane 34 is referred to in FlyBase by the symbol Dmel\Tom34 (CG2708, FBgn0010812). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:3859027..3862381. It has the cytological map location 84E9. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: binding. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 947 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial outer membrane translocase complex [ISS]
    Biological Process: NONE FOUND
    Molecular Function: binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTNTINSEEV SDAGSYKDKG NEAFKASRWE EAVEHYGKAI KAGSKHKELA VFYKNRAAAY  60
   61 LKLGKYENAV EDCTESLKAA PGDPKALFRR AQAYEALEKF EEAYKDATAL FKADPGNKTV 120
  121 QPMLQRLHVV VEERSARNAK TSTKVKQMMD LTFDLATPID KRRAAANNLV VLAKEQTGAE 180
  181 LLYKDHCIAK VASLTKVEKD QDIYVNMVHL VAALCENSVE RTKGVLTELG VPWFMRVLDQ 240
  241 KHENCVSTAQ FCLQTILNAL SGLKNKPDSK PEKELCTRNN REIDTLLTCL VYSITDRTIS 300
  301 GAARDGVIEL ITRNVHYTAL EWAERLVEIR GLCRLLDVCS ELEDYKYESA MDITGSSSTI 360
  361 ASVCLARIYE NMYYDEAKAR FTDQIDEYIK DKLLAPDMES KVRVTVAITA LLNGPLDVGN 420
  421 QVVAREGILQ MILAMATTDD ELQQRVSCEC LIAASSKKDK AKALCEQGVD ILKRLYHSKN 480
  481 DGIRVRALVG LCKLGSYGGQ DAAIRPFGDG AALKLAEACR RFLIKPGKDK DIRRWAADGL 540
  541 AYLTLDAECK EKLIEDKASI HALMDLARGG NQSCLYGVVT TFVNLCNAYE KQEMLPEMIE 600
  601 LAKFAKQHIP EEHELDDVDF INKRITVLAN EGITTALCAL AKTESHNSQE LIARVLNAVC 660
  661 GLKELRGKVV QEGGVKALLR MALEGTEKGK RHATQALARI GITINPEVSF SGQRSLDVIR 720
  721 PLLNLLQQDC TALENFESLM ALTNLASMNE SVRQRIIKEQ GVSKIEYYLM EDHLYLTRAA 780
  781 AQCLCNLVMS EDVIKMFEGN NDRVKFLALL CEDEDEETAT ACAGALAIIT SVSVKCCEKI 840
  841 LAIASWLDIL HTLIANPSPA VQHRGIVIIL NMINAGEEIA KKLFETDIME LLSGLGQLPD 900
  901 DTRAKAREVA TQCLAAAERY RIIERSDNAE IPDVFAENSK ISEIIDD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..477] PSI-BLAST 25.154902 PP5 structure
    2 View Details [478..947] PSI-BLAST 98.154902 Importin alpha

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • structural constituent of muscle
    		•  2.91086263632625 bayes_pls_golite062009
  • binding
    		•  2.09193012129784 bayes_pls_golite062009
  • protein binding
    		•  1.52807685989528 bayes_pls_golite062009
  • protein serine/threonine phosphatase activity
    		•  1.09206313505563 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  0.855511277899989 bayes_pls_golite062009
  • phosphatase activity
    		•  0.709873667529051 bayes_pls_golite062009
  • phosphoprotein phosphatase activity
    		•  0.521298686118866 bayes_pls_golite062009
    2
    Term Confidence Notes
  • binding
    		•  2.4389817190572 bayes_pls_golite062009
  • protein binding
    		•  1.63705839411934 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.01396453014861 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.773975545005505 bayes_pls_golite062009
  • actin binding
    		•  0.572473732371314 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.294257360897755 bayes_pls_golite062009
  • RNA binding
    		•  0.0287526191298597 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle